Results 51 to 60 of about 143,004 (304)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

DC Transformers in DC Distribution Systems

Energies, 2023
With the rapid development of power electronics technology and its successful application, many demonstration projects of medium/low-voltage DC (M-LVDC) distribution systems have been constructed.
Yangfan Chen, Yu Zhang
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Research on transformer vibration monitoring and diagnosis based on Internet of things

Journal of Intelligent Systems, 2021
A recent advent has been seen in the usage of Internet of things (IoT) for autonomous devices for exchange of data. A large number of transformers are required to distribute the power over a wide area.
Wang Zhenzhuo, Sharma Amit
doaj   +1 more source

SIMULASI PENGEMBANGAN TRAFO DISTRIBUSI BERDASARKAN PERTUMBUHAN BEBAN MENGGUNAKAN MODEL DKL 3,2 DAN SOFTWARE ETAP 7.0.0 TAHUN 2012 – 2016 DI UPJ BATANG [PDF]

, 2012
Electric energy infrastructure as one of the livelihood of the people concerning the distribution of electrical energy must be able to guarantee in an amount sufficient, reasonable price and good quality.
Mahardika, Dhimas, nugroho, agung, Sukmadi, Tedjo   +2 more
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Long‐Term Comprehensive Risk Assessment of Distribution Transformers Based on Random Forests and Global Climate Models

IET Renewable Power Generation
With the increasing integration of distributed photovoltaics (PV), the risk profile of distribution transformers is becoming increasingly intertwined with meteorological factors.
Jie Chen, Wanxing Sheng, Lingyun Gu, Ge Zheng, Yan Wu, Shilei Guan   +5 more
doaj   +1 more source

Parameter estimation of electric power transformers using Coyote Optimization Algorithm with experimental verification [PDF]

, 2020
In this work, the Coyote Optimization Algorithm (COA) is implemented for estimating the parameters of single and three-phase power transformers. The estimation process is employed on the basis of the manufacturer's operation reports.
Abaza, Amlak, Abdelwanis, Mohamed I, El-Sehiemy, Ragab A, Ibrahim, Mohamed Nabil Fathy, Rezk, Hegazy   +4 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source