Results 71 to 80 of about 143,004 (304)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Applied SciencesShort-circuit resistances are transformer parameters that characterize the electrical load losses and correct operation of these machines. However, the traditional concept of short-circuit resistance, independent of the harmonic frequencies, has been ...
Vicente León-Martínez +3 more
doaj +1 more source
Enhanced Electric Vehicle Integration in the UK Low Voltage Networks with Distributed Phase Shifting Control [PDF]
, 2019 Electric vehicles (EV) have gained global attention due to increasing oil prices and rising concerns about transportation-related urban air pollution and climate change.
Denai, Mouloud, Vega-Fuentes, Eduardo
core +3 more sources
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
A Review of Health Assessment Techniques for Distribution Transformers in Smart Distribution Grids
Applied Sciences, 2020 Due to the large number of distribution transformers in the distribution grid, the status of distribution transformers plays an important role in ensuring the safe and reliable operation of the these grids. To evaluate the distribution transformer health,
Quynh T. Tran +6 more
doaj +1 more source
, 2018 pandapower is a Python based, BSD-licensed power system analysis tool aimed at automation of static and quasi-static analysis and optimization of balanced power systems.
Braun, Martin +7 more
core +1 more source
Supporting group maintenance through prognostics-enhanced dynamic dependability prediction [PDF]
, 2017 Condition-based maintenance strategies adapt maintenance planning through the integration of online condition monitoring of assets. The accuracy and cost-effectiveness of these strategies can be improved by integrating prognostics predictions and ...
Aizpurua, J. I. +9 more
core +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source