Results 71 to 80 of about 168,603 (302)

Un approccio di equilibrio finanziario di lungo periodo ai problemi di un sistema pensionistico a ripartizione

Moneta e Credito, 2013
The article compares the distributional features of pay-as-you-go and fully funded pension systems. It analyses in particular the tendencies of pay-as-you-go systems to offer vary high benefits and internal rate of returns at the beginning of their ...
A. NICCOLI
doaj   +1 more source

The ENCODE Imputation Challenge: a critical assessment of methods for cross-cell type imputation of epigenomic profiles

Genome Biology, 2023
A promising alternative to comprehensively performing genomics experiments is to, instead, perform a subset of experiments and use computational methods to impute the remainder.
Jacob Matthew Schreiber, Carles A. Boix, Jin wook Lee, Hongyang Li, Yuanfang Guan, Chun-Chieh Chang, Jen-Chien Chang, Alex Hawkins-Hooker, Bernhard Schölkopf, Gabriele Schweikert, Mateo Rojas Carulla, Arif Canakoglu, Francesco Guzzo, Luca Nanni, Marco Masseroli, Mark James Carman, Pietro Pinoli, Chenyang Hong, Kevin Y. Yip, Jefrey P. Spence, Sanjit Singh Batra, Yun S. Song, Shaun Mahony, Zheng Zhang, Wuwei Tan, Yang Shen, Yuanfei Sun, Minyi Shi, Jessika Adrian, Richard S. Sandstrom, Nina P. Farrell, Jessica M. Halow, Kristen Lee, Lixia Jiang, Xinqiong Yang, Charles B. Epstein, J. Seth Strattan, Bradley E. Bernstein, Michael P. Snyder, Manolis Kellis, William S. Noble, Anshul Bharat Kundaje, ENCODE Imputation Challenge Participants   +42 more
doaj   +1 more source

Distributional effects and individual differences in L2 morphology learning [PDF]

, 2016
Second language (L2) learning outcomes may depend on the structure of the input and learners’ cognitive abilities. This study tested whether less predictable input might facilitate learning and generalization of L2 morphology while evaluating ...
Brooks, Patricia J., Kempe, Vera, Kwoka, Nicole   +2 more
core   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Energy balancing of covariate distributions

Journal of Causal Inference
Bias in causal comparisons has a correspondence with distributional imbalance of covariates between treatment groups. Weighting strategies such as inverse propensity score weighting attempt to mitigate bias by either modeling the treatment assignment ...
Huling Jared D., Mak Simon
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Age-Based Dynamics of a Stable Circulating Cd8 T Cell Repertoire Component

Frontiers in Immunology, 2019
T-cell memory to pathogens can be envisioned as a receptor-based imprint of the pathogenic environment on the naïve repertoire of clonotypes. Recurrent exposures to a pathogen inform and reinforce memory, leading to a mature state.
Elena N. Naumova, Maryam B. Yassai, Wendy Demos, Erica Reed, Melissa Unruh, Dipica Haribhai, Calvin B. Williams, Yuri N. Naumov, Jack Gorski   +8 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A review of flood mitigation benefit-cost analyses’ inclusiveness of environmental watershed effects and environmental vulnerability: gaps in progress towards more resilient flood hazard decision-making

Frontiers in Built Environment
US and EU flood mitigation policy both incorporate considerations of costs and benefits, and in recent years have taken steps to encourage accounting for positive and negative effects on vulnerable populations, broader non-market environmental impacts ...
Fahmida Akhter, Sapana Bastola, Jerrod Penn, Thomas Douthat, Thomas Douthat   +4 more
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source