Results 121 to 130 of about 569 (214)

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Robust topology and dispatch optimization for renewable distribution networks with electric vehicle mobility uncertainty

Scientific Reports
The increasing interdependence between power distribution networks and transportation systems introduces unprecedented operational complexity under high renewable penetration and stochastic electric vehicle (EV) mobility.
Liang Xu, Jianjian Jiang, Shizhao Hu, Tianlin Wang, Jiadu Dong   +4 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Distributionally Robust Kalman Filter

CoRR
We study state estimation for discrete-time linear stochastic systems under distributional ambiguity in the initial state, process noise, and measurement noise. We propose a noise-centric distributionally robust Kalman filter (DRKF) based on Wasserstein ambiguity sets imposed directly on these distributions.
Minhyuk Jang, Astghik Hakobyan, Insoon Yang   +2 more
openaire   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Flow-Based Distributionally Robust Optimization

IEEE Journal on Selected Areas in Information Theory
IEEE Journal on Selected Areas in Information Theory (JSAIT).
Chen Xu, Jonghyeok Lee, Xiuyuan Cheng, Yao Xie 0002   +3 more
openaire   +2 more sources

A Differential Planning Strategy for Distribution Network Resilience Enhancement Considering Decision Dependence Uncertainty

Energies
To reduce the impact of extreme natural disasters on urban distribution networks and improve the interpretability of planning decisions, this paper proposes a distributionally robust planning strategy for distribution networks that considers decision ...
Xuming Chen, Le Liu, Xiaoning Kang
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Distributionally robust optimization of load balancing in new distribution network considering loop closing current constraints

Diance yu yibiao
In view of the influence of the uncertainty of distributed PV(photovoltaic) output on the loop closing operation of new distribution network, a distributionally robust optimization model of load balancing in new distribution network considering loop ...
CUI Jiao, SU Ji, ZHANG Juncheng, ZHAO Zhongyuan, ZHAN Fengnan, LIU Haixin   +5 more
doaj   +1 more source