Should we return to probability distributions to represent interfacial reactivity? [PDF]
Criscenti LJ.
europepmc +1 more source
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Forecasting World Crop Yields as Probability Distributions [PDF]
Traditionally, agricultural forecasts, whether for the coming year or several years into the future, have been based on assumptions of normal weather and trend crop yields.
Ferris, John N.
core
Distributionally Regulated Functions in Several Variables [PDF]
Ricardo Estrada
doaj +1 more source
Reject common measures like d' and Corrected Recognition, embrace d<sub>a</sub>: Simulation explorations of single- and multi-point recognition measures of sensitivity. [PDF]
Levi A +3 more
europepmc +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
CROP INSURANCE VALUATION UNDER ALTERNATIVE YIELD DISTRIBUTIONS [PDF]
Considerable disagreement exists about the most appropriate characterization of farm-level yield distributions. Yet, the economic importance of alternate yield distribution specifications on insurance valuation, product designs and farm-level risk ...
Schnitkey, Gary D. +3 more
core
Making Ends Meet or Just Meeting at the Ends? Assessing End-to-End Distance in Folded RNA Sequences and Other Branched Structures. [PDF]
Greenwood T, Heitsch C.
europepmc +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source

