Results 111 to 120 of about 107,677 (337)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Distributive Semimodules: Theory, Properties, and Extensions
, 2023 Ali Hasan Abdulkhaliq +1 more
openalex +2 more sources
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
آموزش مهندسی ایرانThe speed of growth and change of knowledge in engineering fields, has led to the need for new approaches. Connectivism theory has solved this problem by placing the learner at the center of learning and providing a new definition of learning. MOOCs have
Fatemeh Sharzehee +4 more
doaj +1 more source
INEQUALITY AND SOCIAL AND ECONOMIC SAFETY [PDF]
Экономика региона, 2008 The strong, dynamically developing economy is the major component and a basis of national safety. To number of factors, direct image braking economic development, the sharp social and economic disproportions arisen during reforms spent for the country ...
A.J. Shevjakov
doaj
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Humanities & Social Sciences CommunicationsThe phenomenon of “involutionary competition” in the East Asian region has emerged as a critical challenge impacting socioeconomic development. How to change the involutionary behavior effectively while enhancing well-being and societal competitiveness ...
Xiaoliang Xu +4 more
doaj +1 more source
Congruence lattices of free lattices in non-distributive varieties
, 2005 We prove that for any free lattice F with at least $\aleph\_2$ generators in any non-distributive variety of lattices, there exists no sectionally complemented lattice L with congruence lattice isomorphic to the one of F.
Ploscica, Miroslav +2 more
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