Results 81 to 90 of about 107,677 (337)
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
A uniform refinement property for congruence lattices
, 2005 The Congruence Lattice Problem asks whether every algebraic distributive lattice is isomorphic to the congruence lattice of a lattice. It was hoped that a positive solution would follow from E. T. Schmidt's construction or from the approach of P. Pudlak,
Wehrung, Friedrich
core
A class of infinite convex geometries [PDF]
, 2015 Various characterizations of finite convex geometries are well known. This note provides similar characterizations for possibly infinite convex geometries whose lattice of closed sets is strongly coatomic and lower continuous. Some classes of examples of
Adaricheva, Kira, Nation, J. B.
core +2 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Permutation groups, partition lattices and block structures
Forum of Mathematics, SigmaLet G be a finite transitive permutation group on $\Omega $ . The G-invariant partitions form a sublattice of the lattice of all partitions of $\Omega $ , having the further property that all its elements are uniform (that is, have all parts ...
Marina Anagnostopoulou-Merkouri +2 more
doaj +1 more source
A survey of recent results on congruence lattices of lattices [PDF]
, 2005 We review recent results on congruence lattices of (infinite) lattices. We discuss results obtained with box products, as well as categorical, ring-theoretical, and topological ...
Tuma, Jiri, Wehrung, Friedrich
core
Distributive lattices with strong endomorphism kernel property as direct sums [PDF]
, 2021 Saeid Bagheri
openalex +1 more source
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Governance in Blockchain Technologies & Social Contract Theories
Ledger, 2016 This paper is placed in the context of a growing number of social and political critiques of blockchain technologies. We focus on the supposed potential of blockchain technologies to transform political institutions that are central to contemporary human
Wessel Reijers +2 more
doaj +1 more source