Results 121 to 130 of about 2,278 (280)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
On the relations between distributive computability and the BSS model
, 2007 This paper presents an equivalence result between computability in the BSS model and in a suitable distributive category. It is proved that the class of functions R m !
Sebastiano Vigna
core
Chain algebras of finite distributive lattices
We introduce a family of toric algebras defined by maximal chains of a finite distributive lattice. Applying results on stable set polytopes we conclude that every such algebra is normal and Cohen-Macaulay, and give an interpretation of its Krull ...
Gasanova, Oleksandra, +3 more
core +1 more source
Effect algebras and ring-like structures
, 2003 The dichotomic physical quantities, also called propositions, can be naturally associated to maps of the set of states into the real interval [0,1]. We show that the structure of effect algebra associated to such maps can be represented by quasiring ...
Beltrametti, Enrico, Maczyński, Maciej
core +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
The Bordalo order on a commutative ring
, 1999 summary:If $R$ is a commutative ring with identity and $\leq$ is defined by letting $a\leq b$ mean $ab=a$ or $a=b$, then $(R,\leq)$ is a partially ordered ring.
Smith, Frank A. +2 more
core
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source