Results 131 to 140 of about 13,454 (259)

Strengthening supply chains for pathogen genomic surveillance in Asia. [PDF]

BMJ Glob Health
Stona AC, Khoo YK, Moe, Wulandari S, Agoramurthy S, Getchell M, Mak TM, Pang J, Liu EJ, Selva Kumar S, Lim JC, Smith GJD, Bertholet A, Garg A, Harsono S, Magner M, Qadri F, Shirin T, Andalucia LR, Munira SL, Xangsayarath P, Robinson MT, Setk S, Myat Tu H, Arunkumar G, Jha R, Amir A, Ikram A, Nisar I, Dizon T, Saloma C, Malavige NG, De Alwis R, Pronyk PM.   +33 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Influence of Hydrogen-Based Direct Reduction Shaft Furnace Interior Structure on Shaft Furnace Performance. [PDF]

Materials (Basel)
Xue Q, Liao H, Zhang J, Li K.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Computational Fluid Dynamics Analysis of Falling Film Hydrodynamics in Spiral-Wound Heat Exchangers. [PDF]

ACS Omega
Dong L, Dai X, Liu F, Kong L, Zhang R, Wu X, Zhu T.   +6 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Correction: Disposal practices of cigarettes and electronic nicotine products among adults, findings from Wave 6 (2021) of the PATH Study. [PDF]

PLoS One
Sharma E, Dubsky J, Garcia-Rosales KV, Halenar M, Benson AF, Maki A, Ruybal AL, Morse AL, Sawdey MD, Alrefai-Kirkpatrick R, Skara S, Ntim SA, Chang HW, Aung TW, Kimmel HL, Pearson JL, Bansal-Travers M, Taylor KA, Hyland A, Novotny TE.   +19 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

A multi-city outbreak of Salmonella Enteritidis infections linked to bakery products, Republic of Korea. [PDF]

Osong Public Health Res Perspect
Kim DS, Seo SY, Kim DH, Woo YH, Lee D, Yang SJ, Kim J, Shin E, Jung B, Lee E, Lee MJ, Park YJ.   +11 more
europepmc   +1 more source