Results 181 to 190 of about 13,454 (259)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Developing and evaluating a community-driven intervention to promote uptake of HIV and contraception services among students enrolled in colleges and universities in Zimbabwe. [PDF]

J Int AIDS Soc
Kuguyo O, Mancitshana L, Mangenah C, Tumushime MK, Ruhode N, Matsikire E, Kalweo J, Terris-Prestholt F, Cowan FM, Sibanda EL.   +9 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

"I heard at home. The leader came by to inform". The role of community leaders and community distributors in promoting uptake of seasonal malaria chemoprevention in Nampula Province, Mozambique: a qualitative study. [PDF]

BMC Public Health
Sitoe M, Candrinho B, Baker K, Machava J, Passe R, Tarquino IAP.   +5 more
europepmc   +1 more source

Perceptions and Needs of Primary Healthcare Providers Regarding Electricity Shortages and Blackouts: A Qualitative Study Using a Realistic Narrative Approach. [PDF]

Int J Public Health
Baquet E, Tarteret P, Deschamps A, Filali A, Foley RA, D'Acremont V.   +5 more
europepmc   +1 more source

Nephrology in Turbulence: Workforce Strain, Dialysis Gaps, and System Fragility in Nepal After the 2025 Gen Z Protests. [PDF]

Kidney Int Rep
Yogi RN, Kanjanabuch T, Giri P, Singh AP, Sharma D.   +4 more
europepmc   +1 more source

Disposal of expired medicines in Jordan: Practices of community pharmacists. [PDF]

PLoS One
Hamed R, H Hasan DH, Hammad A, Hasan Ibrahim A.   +3 more
europepmc   +1 more source

Playing With Fire: the Effects of Institutional Dysfunctions in Postdisaster Business Recovery. [PDF]

Risk Anal
Amankwah-Amoah J, A Debrah Y.
europepmc   +1 more source

An Investigation of an Outbreak of <i>Salmonella</i> Newport Infections Linked to Melons from Southwest Indiana-United States, 2023. [PDF]

Foodborne Pathog Dis
Cataldo N, Schwensohn C, Kirchner M, Jenkins E, Jemaneh T, Seelman S, Dey M, Hamblin C, Brillhart D, Goodman A, Nolte K, Baker A, Jackson T, Literman B, Bell RL, Hawkins T, Gieraltowski L, Salter M, Viazis S.   +18 more
europepmc   +1 more source

Critical considerations on the article by Bobelyak et al. (2025) "Bone mineral density assessment using radiofrequency echographic multispectrometry (REMS) in patients before and after total hip replacement"; https://doi.org/10.1007/s00198-025-07685-w. [PDF]

Osteoporos Int
Argentieri A, Conversano F, Casciaro S.
europepmc   +1 more source