Results 201 to 210 of about 2,246,072 (312)

Acceptability, feasibility and perceived benefits of integrating mental health and psychosocial support (MHPSS) into disease outbreak response in Western Uganda: a qualitative process evaluation study. [PDF]

BMJ Public Health
Yirdaw BA, Kalani K, Alkasaby M, Zhao Y, Wang L, Kwagala C, Mfitundinda E, Abbo C, Haque F, Eaton J.   +9 more
europepmc   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

Distribution of HIV-1 subtypes and molecular transmission networks among HIV/AIDS cases in Dinghai District, Zhoushan, China. [PDF]

Medicine (Baltimore)
Wang Y, Zhang B, Gu S, Yu Q, Chen J.
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Malaria Morbidity and Its Association With Indoor Residual Spraying in Amolatar District, Uganda: A Retrospective Ecological Study Using Routine DHIS2 Data. [PDF]

Health Sci Rep
Orech S, Okolimong C, Osir E, Ajwang E, Okia D.   +4 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Pattern recognition and spatial differentiation of built environment around urban sports facilities from perspective of facility hierarchy: a case study of Changsha city. [PDF]

Front Public Health
Zhang G, Qiu S, Ding G.
europepmc   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Persistent spatial hotspots and socioeconomic inequalities of snakebite envenoming in Peru: A nationwide spatiotemporal analysis, 2010-2025. [PDF]

PLoS Negl Trop Dis
Grados Vásquez M, Guerra Blas JC, Salcedo-Prudencio A, Santos Siqueira T, Monteiro W, Amaya Parra JA, Martinez-Espinosa FE.   +6 more
europepmc   +1 more source