Results 51 to 60 of about 1,997,090 (294)

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

District heating network topology optimization and optimal co-planning using dynamic simulations

open access: yesAdvances in Applied Energy
District heating networks play a critical role in the transition of the heating supply of buildings to renewable sources. The transition from coal-fired or gas-fired generation units to heat pumps requires new planning methods for district heating ...
Jonathan Vieth   +2 more
doaj   +1 more source

Framework for the Automated Identification of Possible District Heating Separations to Utilise Present Heat Sources Based on Existing Network Topology

open access: yesEnergies, 2022
The ambitious climate targets of the European Union emphasise the necessity to reduce carbon dioxide emissions in the building sector. Therefore, various sustainable heat sources should be used in existing district heating systems to cover the heat ...
Jan Stock, André Xhonneux, Dirk Müller
doaj   +1 more source

Digitalization of district heating and cooling systems

open access: yesEnergy Reports, 2021
District heating and cooling (DHC) networks are traditionally operated with a limited number of controls to secure the required supply task and to optimize economics and ecologic performance. An optimized heat generation and overall network operation is possible with more information on the demand and flexibility options.
openaire   +2 more sources

Thermoeconomic approach for the analysis of low temperature district heating systems [PDF]

open access: yes, 2012
In this paper a thermoeconomic analysis of district heating systems is performed. The analysis aims at comparing possible options to supply heat to the users, using low temperature networks.
Albana Kona   +2 more
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Reduction of the return temperature in district heating systems with an ammonia-water absorption heat pump

open access: yesCase Studies in Thermal Engineering, 2018
In this study, a new setup for the reduction of the return temperature in district heating systems will be presented. For this purpose, an ammonia-water absorption heat pump will be integrated within a district heating substation and theoretically ...
N. Mirl, F. Schmid, K. Spindler
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Integration of Heat Pumps in Buildings and District Heating Systems—Evaluation on a Building and Energy System Level

open access: yesEnergies, 2022
The use of heat pumps in buildings is one of the best and often the only option for the decarbonization of the building stock. District heating seems a promising solution in urban areas and in existing buildings when the use of heat pumps is restricted ...
Fabian Ochs   +2 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

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