Results 41 to 50 of about 576,419 (267)
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
This study evaluates the potential of Boston Ivy (Parthenocissus tricuspidata) to reduce building surface temperature in a mid-latitude North American city center where vine use for this purpose is uncommon.
Andrew A. Millward, Michelle Blake
doaj +1 more source
Quantifying carbon and species dynamics under different fire regimes in a southeastern U.S. pineland
Forests have a prominent role in carbon sequestration and storage. Climate change and anthropogenic forcing have altered the dominant characteristics of some forested ecosystems through changes to their disturbance regimes, particularly fire.
Steven A. Flanagan +12 more
doaj +1 more source
Long-Term Suppression of Hardwood Regeneration by Chinese Privet (Ligustrum sinense)
Native hardwood regeneration in the southeast United States is hindered by repeat disturbance events and the presence of invasive species. Our study aimed to determine the ability of native species in an unmanaged urban forest fragment to persist ...
Taylor N. Turner +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The Rapid Initial Community Builder (RICB) V1.1 for LANDIS-II
Forest succession, or ecosystem process models, can aid in many land management decisions as they inherently incorporate ecological processes to predict how disturbances impact the resilience of the forest and its potential future structure.
Steven A Flanagan +7 more
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

