Results 81 to 90 of about 242,416 (261)
Soil carbon and plant richness relationships differ among grassland types, disturbance history and plant functional groups. [PDF]
Oecologia, 2021 Anacker BL +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Unilateral optic disc swelling: an atypical presentation for a large frontal meningioma
Panorama of Emergency MedicineIntracranial space occupying lesions pose a frequent diagnostic dilemma from history and clinical signs alone. They remain an important differential in those presenting with neurological or ophthalmological symptoms.
Pourya Pouryahya +2 more
doaj +1 more source
Allocating species in Grime’s strategy space: an alternative to trait-based approaches
Botanical Sciences, 2019 Background: The three primary-strategy theory proposed by Grime identifies stress and disturbance as key environmental factors leading to the emergence of distinct plant strategies. These are defined by a combination of stress and disturbance tolerance.
Fernando Pedraza, Carlos Martorell
doaj +1 more source
A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline
FEBS Open Bio, EarlyView.Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey +4 more
wiley +1 more source
Spatial tree age structure and fire history in two old-growth forests in eastern Fennoscandia
Silva Fennica, 2002 Two near natural old-growth forests, one dominated by Picea abies and the other by Pinus sylvestris, were studied for their fire history, and spatial patterns of trees and tree ages.
Wallenius, Tuomo +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source