Results 41 to 50 of about 2,034,129 (243)

Interoceptive Awareness Mediates Effects of Sleep Disturbance on Pain Outcomes in Chronic Pain Patients

Integrative Medicine Reports
Background: Sleep disorders are common in adults with chronic pain and are multifactorial. Recent evidence suggest sleep disturbance may affect interoceptive awareness (IA) in healthy adults.
Dana Dharmakaya Colgan, Natasha Parman
doaj   +1 more source

Temporal effects of disturbance on community composition in simulated stage‐structured plant communities

Ecology and Evolution, 2018
In an era of global environmental change, understanding how disturbance affects the dynamics of ecological communities is crucial. However, few studies have theoretically explored the potential influence of disturbance including both intensity and ...
Youshi Wang, Shujun Wen, M. D. Farnon Ellwood, Adam D. Miller, Chengjin Chu   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

The persistence of bacterial diversity and ecosystem multifunctionality along a disturbance intensity gradient in karst soil

, 2020
Extensive, progressive rock emergence causes localized variations in soil biogeochemical and microbial properties that may influence the capacity for the regeneration of degraded karst ecosystems.
Kuzyakov, Yakov, Powlson, D. S., Dungait, J. A. J., Quine, Timothy A., Kuzyakov, Y, Xing, K., Tian, Jing, Yang, L., Xing, Kaixiong, Powlson, David, Xue, Yafang, Quine, T. A., Tiana, J., Xue, Y., Yang, Liyang, Tian J., Dungait, Jennifer, Yang L., Powlson D., Dungait J.A.J., Xing K., Dungait, Jennifer A. J., Xue Y., Quine T.A., Kuzyakov Y., Kaixiong Xing, Yakov Kuzyakov, Timothy A. Quine, Jennifer A.J. Dungait, Liyang Yang, Jing Tian, David Powlson, Yafang Xue   +32 more
core   +1 more source

Factors Controlling Species Richness in Alpine Plant Communities: An Assessment of the Importance of Stress and Disturbance [PDF]

, 2002
This study explores whether the high variability of vascular plant diversity among alpine plant communities can be explained by stress and/or disturbance intensities. Species numbers of 14 alpine plant communities were sampled in the Swiss Alps.
Kammer, Peter M., Möhl, Adrian
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

A framework for estimating forest disturbance intensity from successive remotely sensed biomass maps: moving beyond average biomass loss estimates [PDF]

, 2015
Background The success of satellites in mapping deforestation has been invaluable for improving our understanding of the impacts and nature of land cover change and carbon balance.
M Williams (834184), CM Ryan (12158950), TC Hill (21835463)   +2 more
core   +4 more sources

Posterior summaries for the proportion of seals presenting a high intensity reaction, i.e. flushing, to a disturbance source.

, 2022
Posterior summaries for the proportion of seals presenting a high intensity reaction, i.e. flushing, to a disturbance source.
María C. García-Aguilar (4857550), Yolanda Schramm (4857547), Elena Solana-Arellano (13007292), Maria Clara Arteaga (8904440), María Guadalupe Ruiz-Mar (13007289), Gisela Heckel (5345783)   +5 more
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source