Results 131 to 140 of about 1,796,874 (292)

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

The role of wetland vegetation and water connectivity in shaping waterbird populations under human disturbance

Ecological Indicators
The floodplain wetland of Poyang Lake, one of the largest stopover sites for overwintering waterbirds along the East Asian–Australasian Flyway, is experiencing rising human disturbance and rapid landscape changes.
Yirong Wan, Linling Tang, Xuejiao Hou, Hui Lin, Xiaobin Cai, Zihui Huang, Qiangqiang Xu, Yuhong He   +7 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael   +22 more
wiley   +1 more source

ground-disturbance-rates

, 2016
Rates of feral pig ground disturbance from the Waitakere Ranges, Auckland, New Zealand.
Bruce R. Burns (846305), Etherington, Thomas E., Thomas E. Etherington (3289968), Cheryl R. Krull (846304), Krull, Cheryl R., David Choquenot (846306), Choquenot, David, Margaret C. Stanley (552443), Stanley, Margaret C., Burns, Bruce R.   +9 more
core   +1 more source

Changes in Immune‐Inflammation Status and Prognosis in Pregnancy‐Related Cerebral Venous Thrombosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Distinguishing pathological changes from physiological adaptations in pregnancy‐related cerebral venous thrombosis (CVT) is clinically challenging. This study aimed to characterize coagulation, immune‐inflammation, and dehydration status in these patients and assess their prognostic value.
Xiaoming Zhang, Zilin Xu, Ran Duan, Chunxiao Lu, Da Zhou, Chen Zhou, Ran Meng, Xunming Ji   +7 more
wiley   +1 more source

MOESM1 of A framework for estimating forest disturbance intensity from successive remotely sensed biomass maps: moving beyond average biomass loss estimates

, 2016
Additional file 1. A framework for estimating forest disturbance intensity from remotely sensed biomass maps: moving beyond average biomass loss ...
C. Ryan (3402638), M. Williams (2052994), T. Hill (3402635)   +2 more
core   +1 more source

Early Clinical and Cerebrospinal Fluid Predictors of 1‐Year Recurrence in Autoimmune GFAP Astrocytopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A) is an inflammatory central nervous system disorder with variable outcomes. Relapse occurs in a subset of patients, but early predictors remain unclear. We aimed to identify admission‐available features associated with 1‐year recurrence and develop an interpretable ...
Qingting Hong, Yuping Xiao, Yuhan Wu, Ziyuan Huang, Weishan Liang, Li Xiao, Yaqing Shu, Tingting Lu, Yanyu Chang, Wei Qiu, Yuge Wang   +10 more
wiley   +1 more source

Effects of grazing disturbances on soil seed bank diversity in two vegetation types

Global Ecology and Conservation
Soil seed bank (SSB) play an essential role in the restoration and regeneration of plant communities. Grazing is a common disturbance factor that exerts an important effect on the diversity and composition of the SSB community in forests.
Mingmiao Chen, Xin Niu, Wenna Li, Peiyao Liu, Caicai Zhang, Zhipang Huang   +5 more
doaj   +1 more source

transect-disturbance

, 2016
The percentage of ground disturbed by feral pigs along each (arbitrarily named A-W) 200m ground disturbance monitoring transect.Transects were monitored four times (November 2008, September 2009, December 2010 and August ...
Bruce R. Burns (846305), Etherington, Thomas E., Thomas E. Etherington (3289968), Cheryl R. Krull (846304), Krull, Cheryl R., David Choquenot (846306), Choquenot, David, Margaret C. Stanley (552443), Stanley, Margaret C., Burns, Bruce R.   +9 more
core   +1 more source