Results 111 to 120 of about 1,713,738 (281)

Analysis of mesoscopic damage evolution in freeze-thawed sandstone under dynamic disturbance

open access: yesYantu gongcheng xuebao
To investigate the damage evolution of rock masses in cold regions under different disturbance conditions, red sandstone samples are subjected to freeze-thaw cycles and dynamic disturbance tests.
ZHANG Jiafan1 , DAI Chaofan 1, ZHANG Huimei 1, CHEN Shiguan 2, HAO Lele 1, YUAN Chao 1
doaj   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou   +16 more
wiley   +1 more source

Functional leaf traits of understory species: strategies to different disturbance severities

open access: yesBrazilian Journal of Biology
The specific leaf area (SLA) has been related to environmental disturbances, showing a positive correlation between the disturbances intensities and SLA in a plant community.
J. Prado Júnior   +5 more
doaj   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky   +5 more
wiley   +1 more source

Disturbance and temporal variability in invertebrate assemblages in two South African rivers [PDF]

open access: yes, 2009
Includes abstract.This thesis presents an examination of the relationship between floods as disturbances, the disturbance regime and the temporal dynamics of invertebrate assemblages, over the short term and at intra- and inter-annual time scales in the ...
Ractliffe, Sylvia Georgiana
core   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias   +3 more
wiley   +1 more source

Smart ring-based assessment of physical activity intensity and sleep disturbances in older adults with mild cognitive impairment

open access: yesDigital Health
Objective Sleep disturbance is common in older adults with mild cognitive impairment (MCI) and is linked to poorer cognitive and overall health, but prior evidence is mixed and often based on self-report.
Jungjoo Lee, Junhyoung Kim
doaj   +1 more source

On the uncertain intensity estimate of the 1859 Carrington storm

open access: yesJournal of Space Weather and Space Climate
A study is made of the intensity of the Carrington magnetic storm of September 1859 as inferred from visual measurements of horizontal-component geomagnetic disturbance made at the Colaba observatory in India.
Love Jeffrey J.   +3 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

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