Results 91 to 100 of about 135,485 (258)

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Prevention of natural grassland invasion by Eragrostis plana Nees using ecological management practices

Revista Brasileira de Zootecnia, 2012
The objective of this research was to evaluate the effects of different types of disturbance on the ability of the natural grassland to avoid the invasion of Eragrostis plana Nees (South African lovegrass).
Telmo Focht, Renato Borges de Medeiros
doaj   +1 more source

[Acid-base disturbances in intensive-care patients].

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2010
Acid-base disturbances may cause a variety of symptoms, multi-organ failure and compromised immune defense. The aim of this paper is to provide an overview of acid-base disturbances in intensive-care patients.The article is based on a non-systematic search in Pub Med, a textbook on intensive care and the authors' clinical experience.The Henderson ...
Nils, Smith-Erichsen, Johan, Kofstad, Baard, Ingvaldsen   +2 more
openaire   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Understanding Disturbance Regimes From Patterns in Modeled Forest Biomass

Journal of Advances in Modeling Earth Systems
Natural and anthropogenic disturbances are important drivers of tree mortality, shaping the structure, composition, and biomass distribution of forest ecosystems.
Siyuan Wang, Hui Yang, Sujan Koirala, Matthias Forkel, Markus Reichstein, Nuno Carvalhais   +5 more
doaj   +1 more source

Analysis of mesoscopic damage evolution in freeze-thawed sandstone under dynamic disturbance

Yantu gongcheng xuebao
To investigate the damage evolution of rock masses in cold regions under different disturbance conditions, red sandstone samples are subjected to freeze-thaw cycles and dynamic disturbance tests.
ZHANG Jiafan1 , DAI Chaofan 1, ZHANG Huimei 1, CHEN Shiguan 2, HAO Lele 1, YUAN Chao 1
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Functional leaf traits of understory species: strategies to different disturbance severities

Brazilian Journal of Biology
The specific leaf area (SLA) has been related to environmental disturbances, showing a positive correlation between the disturbances intensities and SLA in a plant community.
J. Prado Júnior, I. Schiavini, V. Vale, S. Lopes, C. Arantes, AP. Oliveira   +5 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source