Results 171 to 180 of about 179,181 (346)

PDIA6 promotes the cell proliferation of ESCC by enhancing the disulfide bond formation in TRAF4. [PDF]

Cell Mol Biol Lett
Chen Y, Zhang W, Chen Y, Li X, Shi Y, Yuan Q, Han R, Zhang Y, Zhao X, Hu Y, Zhang C, Dong Z, Lee MH, Kim MO, Dong Z, Jiang Y, Liu K.   +16 more
europepmc   +1 more source

Mitochondrial Disulfide Bond Formation Is Driven by Intersubunit Electron Transfer in Erv1 and Proofread by Glutathione [PDF]

, 2010
Melanie Bien, Sebastian Longen, Nikola Wagener, Ilona Chwalla, Johannes M. Herrmann, Jan Riemer   +5 more
openalex   +1 more source

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

Advanced Science, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang, Wentao Si, Youxue Zhang, Jialin Liu, Huaixi Zhang, Yafei Li, Hongmeng Su, Wei Jiang, Zhishan Ding, Lihong Wang   +9 more
wiley   +1 more source

QSOX1: A Mysterious Golgi-Localized Disulfide Bond Catalyst and an Emerging Cancer Regulator. [PDF]

Cancers (Basel)
Wang S, Xiao GY, Tan X.
europepmc   +1 more source

Intra- and Inter-Subunit Disulfide Bond Formation Is Nonessential in Adeno-Associated Viral Capsids

, 2021
Nikolay V. Dokholyan, Aravind Asokan, Nagesh Pulicherla, Pradeep Kota   +3 more
openalex   +1 more source

A Bioinspired Three‐Dimensional High‐Curvature Nano‐Interface Integrated Microfluidic Chip for Small Extracellular Vesicles Enrichment and Machine Learning‐Assisted Prostate Cancer Precision Diagnosis

Advanced Science, EarlyView.
A biotin‐modified artificial insertion peptide functionalized three‐dimensional high‐curvature‐TiO2 nano‐interface was engineered in a microfluidic chip to improve the isolation efficiency of small extracellular vesicles (sEVs). This chip balanced affinity, releasability, and extendibility, enabling high‐throughput recovery of sEVs for downstream ...
Le Wang, Yizhong Liang, Manan Sulaiman, Jiaqi Du, Ming Jiang, Zhihua Wang, Xu Yu, Li Xu   +7 more
wiley   +1 more source

Molecular Mechanism of Disulfide Bond Healing and Network Repair in Epoxy Vitrimers Revealed by Quantum Chemical and Molecular Dynamics Simulations. [PDF]

Polymers (Basel)
Uyama T, Kishimoto N, Oya Y, Murashima T, Koyanagi J.   +4 more
europepmc   +1 more source

Cysteine Reactivity Profiling Illuminates Monoclonal Antibody Disulfide Bond Reduction Mechanisms in Biopharmaceutical Process Intermediates [PDF]

Taku Tsukidate, Zhenshu Wang, Andrew Hsieh, Patricia Rose, Xuanwen Li   +4 more
openalex   +1 more source

Tumor‐Derived Exosomes Deliver Membrane‐Bound Fgl2 to Activate FcγRIIB‐Mediated Immunosuppression in Myeloid‐Derived Suppressor Cells

Advanced Science, EarlyView.
This study reveals that the Fgl2‐FcγRIIB signaling axis is a key mechanism by which MDSCs mediate tumor immune evasion. Tumor‐derived exosomes systemically activate MDSCs via this pathway, positioning this axis as a promising broad‐spectrum target for cancer immunotherapy.
Fenglin Lin, Dingqin Cai, Chunli Jian, Yaxian Qi, Linpeng Zheng, Qiao Yang, Longyao Zhang, Diangang Chen, Lingchen Li, Ping Cai, Lingyou Sun, Luping Zhang, Jianguo Sun   +12 more
wiley   +1 more source

Disulfide Bond Mapping of Follitropin Delta, a Recombinant Follicle Stimulating Hormone (rFSH), by X-Ray Crystallography. [PDF]

Pharmaceuticals (Basel)
Kalson D, Joseph JS, Nudelman H, Kamhi E, Bakshi S.   +4 more
europepmc   +1 more source