We developed a novel domino polymerization to synthesize reductively degradable poly(disulfide)s with tunable side chains. A novel monomer bearing thiolactone and pyridyl disulfide groups reacts with various amines, enabling continuous ring‐opening and disulfide exchange.
Yukiya Kitayama +2 more
wiley +1 more source
Oxidative pathways of apo, partially, and fully Zn(II)- and Cd(II)-metalated human metallothionein-3 are dominated by disulfide bond formation. [PDF]
Yuan AT, Stillman MJ.
europepmc +1 more source
Chemical Metabolomics: Chemical Biology Tools for Advanced Metabolism Investigations
The human metabolism has been investigated for several millennia. The metabolome is known for a high complexity due to a large number of different metabolites that are present at different concentrations. Metabolomics has been developed as a field to investigate the entire human metabolome and to elucidate disease development mechanisms.
Alejandro Torregrosa‐Chinillach +4 more
wiley +1 more source
Reversible Disulfide Bond Cross-Links as Tunable Levers of Phase Separation in Designer Biomolecular Condensates. [PDF]
Mondal M +9 more
europepmc +1 more source
Mechanochemistry Meets Catalysis: Metal Complexes for Greener Organic Transformations
Mechanochemistry is redefining metal catalysis by controlling catalyst formulation, speciation, and deployment. This Review shows how milling, LAG, RAM, and TSE enable rapid metal‐complex assembly, distinctive catalytic manifolds, and scalable synthesis beyond solution chemistry.
Sourav Behera +2 more
wiley +1 more source
Stapling Cysteine[2,4] Disulfide Bond of α-Conotoxin LsIA and Its Potential in Target Delivery. [PDF]
Sun X +6 more
europepmc +1 more source
An extensive disulfide bond network prevents tail contraction in Agrobacterium tumefaciens phage Milano. [PDF]
Sonani RR +11 more
europepmc +1 more source
Mechanism of Methylene Blue Inducing the Disulfide Bond Formation of Tubulin-Associated Unit Proteins. [PDF]
Seo DH +7 more
europepmc +1 more source
The structure of Mycobacterium thermoresistibile MmpS5 reveals a conserved disulfide bond across mycobacteria. [PDF]
Cuthbert BJ +5 more
europepmc +1 more source

