Results 321 to 330 of about 1,312,330 (378)

Accelerating Sono‐Piezoelectric Charge Transport for Antibacterial Therapy and Bone Regeneration by Metal‐Deficient TiO2 Spin‐Polarization Effect

Advanced Science, EarlyView.
The deficient TiO2 (DTO) and Barium titanate (BTO) heterojunction treats osteomyelitis through SDT. The spin‐polarization effect induced by the unpaired spin electrons in Ti atoms can expedite the transfer of ultrasonic piezoelectric charges in BTO, enhancing surface sonocatalytic efficiency.
Chaofeng Wang, Shuilin Wu, Congyang Mao, Liguo Jin, Hanpeng Liu, Yufeng Zheng, Chunyong Liang, Shengli Zhu, Zhaoyang Li, Hui Jiang, Xiangmei Liu   +10 more
wiley   +1 more source

A Two‐Component Pseudo‐Icosahedral Protein Nanocompartment with Variable Shell Composition and Irregular Tiling

Advanced Science, EarlyView.
The structure and assembly principles of a two‐component encapsulin nanocompartment shell are reported. The two‐component protein compartment self‐assembles from two distinct HK97‐fold shell proteins into a pseudo‐icosahedral protein shell with variable composition and irregular tiling.
Cassandra A. Dutcher, Michael P. Andreas, Tobias W. Giessen   +2 more
wiley   +1 more source

Improvement in Noodle Quality and Changes in Microstructure and Disulfide Bond Content through the Addition of Pepper Straw Ash Leachate. [PDF]

Foods
Li X, Wu Y, Li C, Tong S, Zhang L, Jin J.   +5 more
europepmc   +1 more source

Phytophthora Disrupts Plant Immunity by Manipulating Nitric Oxide Homeostasis Through GSNOR Inhibition

Advanced Science, EarlyView.
Phytophthora capsici effector PcRD18 targets tomato GSNOR to disrupt NO homeostasis, promoting S‐nitrosylation of immune proteins like RBOHD. This suppresses ROS bursts and promotes pathogen infection. Mutation of the PcRD18‐binding sites of GSNOR avoids pathogen manipulation and offers a strategy to enhance crop resistance. Abstract Nitric oxide (NO),
Tingting Li, Jing Kang, Haizhu Zhang, Lina Wang, Minghui Lu, Lin Cai, Jianming Li, Matthieu H. A. J. Joosten, Yu Du   +8 more
wiley   +1 more source

Warfarin analogs target disulfide bond-forming enzymes and suggest a residue important for quinone and coumarin binding. [PDF]

J Biol Chem
Chavez D, Amarquaye GN, Mejia-Santana A, Dyotima, Ryan K, Zeng L, Landeta C.   +6 more
europepmc   +1 more source

Near‐Infrared Afterglow Imaging‐Guided Surgical Resection and Synergistic Photodynamic‐Chemo Therapy of Breast Cancer

Advanced Science, EarlyView.
A CDSP NPs theranostic platform assembled from CDs and paclitaxel prodrugs is developed. CDSP NPs have long‐lasting NIR afterglow, penetrate deep tissues, and offer a high signal‐to‐noise ratio, enabling NIR afterglow imaging‐guided precise breast cancer removal to prevent recurrence.
Zixuan Li, Ranran Zhao, Qing Pei, Zhigang Xie, Min Zheng   +4 more
wiley   +1 more source

Differential effects of disulfide bond formation in TEM-1 versus CTX-M-9 β-lactamase. [PDF]

Protein Sci
Villanueva M, Vostal LE, Cohen DN, Biesbrock D, Kuwaye EP, Driver SG, Hart KM.   +6 more
europepmc   +1 more source

Inhibition of Heat Shock Protein 90β by Catalpol: A Potential Therapeutic Approach for Alleviating Inflammation‐Induced Cartilage Injuries in Osteoarthritis

Advanced Science, EarlyView.
The schematic diagram delineates the chondroprotective effects of Ca‐bMSN in OA models. The upper portion of the diagram depicts the synthesis process of Ca‐bMSN. The lower section illustrates the post‐injection of Ca‐bMSN in joint cavity, catalpol released and subsequently mediates the reduction of oxidative stress, ECM catabolism, apoptosis, and ...
Zhenwei Zhou, Binghua Zhang, Lang Liu, Jie Yang, Yuting Wang, Cheng Lv, He Zhang, Yuchi Wei, Zhanliang Jiang, Zeyu Peng, Daqing Zhao, Xiangyang Leng, Xiangyan Li, Hang Su, Haisi Dong   +14 more
wiley   +1 more source

Amyloid Forming Human Lysozyme Intermediates are Stabilized by Non‐Native Amide‐π Interactions

Advanced Science, EarlyView.
Mutational variants of human lysozyme cause fatal systemic amyloidosis by depositing kilograms of protein in the viscera of patients. Central to this process is a partially unfolded protein intermediate state that initiates aggregation into amyloid fibrils.
Minkoo Ahn, Julian O. Streit, Christopher A. Waudby, Tomasz Włodarski, Angelo Miguel Figueiredo, John Christodoulou, Janet R. Kumita   +6 more
wiley   +1 more source

Transfer of disulfide bond formation modules via yeast artificial chromosomes promotes the expression of heterologous proteins in Kluyveromyces marxianus. [PDF]

mLife
Wu P, Mo W, Tian T, Song K, Lyu Y, Ren H, Zhou J, Yu Y, Lu H.   +8 more
europepmc   +1 more source