The Influence of Different Protocols on the Application of the Dithiothreitol Assay in Determining the Oxidative Potential of Ambient Particles [PDF]
ToxicsEnvironmental particulate matter (PM) exposure has been widely recognized for its significant adverse effects on human health. Monitoring PM levels is one of the essential parameters of air quality assessment.
Maja Jovanović +5 more
doaj +7 more sources
Electrochemical Dithiothreitol Assay for Large-Scale Particulate Matter Studies. [PDF]
Aerosol Sci Technol, 2019 Particulate matter (PM) air pollution is associated with human morbidity and mortality. Measuring PM oxidative potential has been shown to provide a predictive measurement between PM exposure and adverse health impacts.
Berg KE +8 more
europepmc +5 more sources
Use of Dithiothreitol Assay to Evaluate the Oxidative Potential of Atmospheric Aerosols
Atmosphere, 2019 Oxidative potential (OP) has been proposed as a useful descriptor for the ability of particulate matter (PM) to generate reactive oxygen species (ROS) and consequently induce oxidative stress in biological systems, which has been recognized as one of the
Huanhuan Jiang +4 more
doaj +3 more sources
Oxidant production from source-oriented particulate matter – Part 1: Oxidative potential using the dithiothreitol (DTT) assay [PDF]
Atmospheric Chemistry and Physics, 2015 Recent epidemiological evidence supports the hypothesis that health effects from inhalation of ambient particulate matter (PM) are governed by more than just the mass of PM inhaled.
J. G. Charrier +5 more
doaj +9 more sources
Development and field testing of an online instrument for measuring the real-time oxidative potential of ambient particulate matter based on dithiothreitol assay [PDF]
Atmospheric Measurement Techniques, 2018 We developed an online instrument for measuring the oxidative potential (OP) of ambient particulate matter (PM) using the dithiothreitol (DTT) assay. The instrument uses a mist chamber (MC) to continuously collect the ambient PM2.5 in water, and then ...
J. V. Puthussery, C. Zhang, V. Verma
doaj +5 more sources
A semi-automated system for quantifying the oxidative potential of ambient particles in aqueous extracts using the dithiothreitol (DTT) assay: results from the Southeastern Center for Air Pollution and Epidemiology (SCAPE) [PDF]
Atmospheric Measurement Techniques, 2015 A variety of methods are used to measure the capability of particulate matter (PM) to catalytically generate reactive oxygen species (ROS) in vivo, also defined as the aerosol oxidative potential.
T. Fang +5 more
doaj +5 more sources
A method for measuring total aerosol oxidative potential (OP) with the dithiothreitol (DTT) assay and comparisons between an urban and roadside site of water-soluble and total OP [PDF]
Atmospheric Measurement Techniques, 2017 An automated analytical system was developed for measuring the oxidative potential (OP) with the dithiothreitol (DTT) assay of filter extracts that include both water-soluble and water-insoluble (solid) aerosol species.
D. Gao +4 more
doaj +4 more sources
Evaluation of Oxidative Potential of Pyrenequinone Isomers by the Dithiothreitol (DTT) Assay
Polycyclic Aromatic Compounds, 2021 Atmospheric quinoid polycyclic aromatic hydrocarbons (PAHQs) have adverse health effects as redox-active species in particulate matter (PM). Several PAHQs are known to be very reactive in the dithiothreitol (DTT) assay; however, it is unclear if ...
R. Okubo, T. Kameda, S. Tohno
semanticscholar +2 more sources
Journal of Hazardous Materials, 2023 Metals in particulate matter (PM) are hypothesized to have enhanced toxicity based on their ability to catalyze reactive oxygen species (ROS) formation. Acellular assays are used to measure the oxidative potential (OP) of PM and its individual components.
J. Yalamanchili, C. Hennigan, B. E. Reed
semanticscholar +3 more sources
Real-Time Measurements of PM2.5 Oxidative Potential Using a Dithiothreitol Assay in Delhi, India [PDF]
Environmental Science & Technology Letters, 2020 The oxidative potential (OP) of ambient particulate matter (PM) is a metric commonly used to link the aerosol exposure to its adverse health effects.
J. Puthussery +12 more
semanticscholar +2 more sources