Results 101 to 110 of about 2,501,958 (326)

Levels of Dry Deposition Submicron Black Carbon on Plant Leaves and the Associated Oxidative Potential

Atmosphere
There is a need for monitoring air pollution associated with black carbon (BC) using a passive monitor is required in remote areas where the measurements are absent.
Ying Xu, Qingyang Liu
doaj   +1 more source

pH and reduction dual-responsive micelles based on novel polyurethanes with detachable poly(2-ethyl-2-oxazoline) shell for controlled release of doxorubicin

Drug Delivery, 2019
We describe a biodegradable amphiphilic polyurethane (PU) with disulfide bonds in the main chain [PEtOz-b-PU(SS)-b-PEtOz]. This multi-block PU was synthesized using poly (ε-caprolactone) diol (PCL-SS-PCL) and poly (2-ethyl-2-oxazoline) (PEtOz-OH) as soft
Leran Bu, Hena Zhang, Kang Xu, Baixiang Du, Caihong Zhu, Yuling Li   +5 more
doaj   +1 more source

Ligand-Specific Regulation of the Endogenous Mu-Opioid Receptor by Chronic Treatment with Mu-Opioid Peptide Agonist [PDF]

, 2013
Since the discovery of the endomorphins (EM), the postulated endogenous peptide agonists of the mu-opioid receptors, several analogues have been synthesized to improve their binding and pharmacological profiles.
Birkás, Erika, Bozó, Beáta, Cinar, Resat, Dochnal, Roberta Beatrix, Fábián, Gabriella, Kicsi, Emese Gabriella, Kékesi, Orsolya, Murányi, Marianna, Mácsai, Mónika, Szabó, Gyula, Szűcs, Mária, Tóth, Géza, Zentai, András   +12 more
core   +3 more sources

Microfluidic Platform for Multiparametric Profiling of Fibrin Permeability, Fibrinolysis, and Cell Invasion

Advanced Functional Materials, EarlyView.
This paper introduces a single‐channel H‐junction microfluidic assay that profiles fibrin's evolving function in repair and thrombosis by measuring, in one ∼3 µL gel, permeability, fibrinolysis kinetics, fibroblast invasion, and clot extension in real time.
Halston Deal, Elizabeth M. Byrnes, Sanika Pandit, Halle J. Cantor, Muskan Aslam, Stacy Ban, Megan Palmisano, Rosemary Bayless, Ashley C. Brown, Michael Daniele   +9 more
wiley   +1 more source

Crystal structure of thioredoxin 1 from Cryptococcus neoformans at 1.8 Å resolution shows unexpected plasticity of the loop preceding the catalytic site

Biochemistry and Biophysics Reports, 2020
An elevated prevalence of cryptococcal infection is a tendency in low-income countries and constitutes a global public health problem due to factors such as the limited efficacy of antifungal therapy and the AIDS/transplant immunocompromised patients ...
Claudia Patricia Bravo-Chaucanés, Ana Karina Rodrigues Abadio, Érika Seki Kioshima, Maria Sueli Soares Felipe, João Alexandre Ribeiro Gonçalves Barbosa   +4 more
doaj   +1 more source

The Effects of Dithiothreitol on DNA

Italian National Conference on Sensors, 2017
With the novel possibilities for detecting molecules of interest with extreme sensitivity also comes the risk of encountering hitherto negligible sources of error.
Søren Fjelstrup, M. B. Andersen, J. Thomsen, Jing Wang, M. Stougaard, F. Pedersen, Y. Ho, M. Hede, B. Knudsen   +8 more
semanticscholar   +1 more source

IgG rheumatoid factors in an enzyme-linked immunosorbent assay using dithiothreitol-treated sera: relation to disease activity in rheumatoid arthritis.

Japanese Journal of Clinical Immunology, 1993
Enzyme-linked immunosorbent assay (ELISA)でIgGリウマトイド因子(RF)を測定する場合, IgM RFに結合したnon-RF IgGをIgG RFと測定する可能性があり,前もって検体を還元処理することが有用とされている.今回われわれは還元剤としてdithiothreitol (DTT)を用い, RA 18例の血清53検体のDTT処理前後のIgG RFをIgG RF測定キットED 001 (エーザイ)で測定し, IgG RF値の変動とRAの疾患活動性との相関を検討した.さらに,ゲル濾過法を用い,還元処理したRF陽性血清中のIgM RFとIgG RFの存在様式に及ぼす影響も検討した.慢性関節リウマチ(RA)の疾患活動性は4項目法によるランスバリーの活動性指数 ...
Yukio Sato, Rika Sato, Kazuo Watanabe, Tomoe Nishimaki, Reiji Kasukawa   +4 more
openaire   +2 more sources

Spatial Patterning of Modular Gelatin‐Peroxide Microspheres in Melt‐Electrowritten Scaffolds Provides Controlled Oxygen Generation and Mitigates Hypoxia and Cytotoxicity

Advanced Healthcare Materials, EarlyView.
A bioassembly approach is described using photo‐crosslinked gelatin‐based microgels containing calcium peroxide (CaO2) to generate oxygen (O2) and enhance cell survival in hypoxic conditions (1% O2). Bioassembly enables spatial patterning of individual CaO2‐laden and mesenchymal stem cell (MSC)‐laden microgels and allows for decoupling and mitigating ...
Axel E. Norberg, F. Max Yavitt, Ezgi Bakirci, Khoon Lim, Tim B. F. Woodfield, Gabriella C. J. Lindberg   +5 more
wiley   +1 more source

Inhibition of Subsets of G Protein-coupled Receptors by Empty Mutants of G Protein α Subunits in Go, G11, and G16 [PDF]

, 2000
We previously reported that the xanthine nucleotide binding Goα mutant, GoαX, inhibited the activation of Gi-coupled receptors. We constructed similar mutations in G11α and G16α and characterized their nucleotide binding and receptor interaction.
Gu, Lingjie, Simon, Melvin I., Yu, Bo
core   +1 more source

Engineering Extracellular Vesicle Production Through Magnetic Ion Channel Activation for Bone Regeneration

Advanced Healthcare Materials, EarlyView.
Magnetic Ion Channel Activation (MICA) enables remote stimulation of mechanosensitive ion channels using functionalised magnetic nanoparticles, enhancing extracellular vesicle (EV) biogenesis is pre‐osteoblasts. MICA desrived EVs exhibit typical nano‐vesicular characteristics but display superior pro‐osteogeneic activity, promoting mesenchymal stem ...
Afeesh Rajan Unnithan, Kenny Man, Kritika, Lee A. Gethings, Christopher J. Hughes, Alicia Keenan, Liam Heaney, Sophie C. Cox, Owen G. Davies, Alicia J. El Haj   +9 more
wiley   +1 more source