Results 151 to 160 of about 2,501,958 (326)

Ambient particle composition and toxicity in 31 major cities in China

open access: yesFundamental Research
Current assessment of air quality or control effectiveness is solely based on particulate matter (PM) mass levels, without considering their toxicity differences in terms of health benefits.
Lu Zhang, Maosheng Yao
doaj   +1 more source

Identifying and improving the fibre-degrading activity of rumen microbe-derived fibrolytic bacteria : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Genetics at Massey University, Manawatū, New Zealand [PDF]

open access: yes, 2017
The dairy industry is extremely important to the New Zealand (NZ) economy, and it accounts for approximately $16.6 billion in exports each year. In NZ, traditional feedstock for cattle, such as grass and hay, consists of cellulose-based fibrous material ...
Atua, Renée Mary Louise
core  

Endogenous Ceramide 24:1 Constrains Th17‐Driven Neutrophilic Inflammation by Antagonizing EP2 Signaling

open access: yesAdvanced Science, EarlyView.
Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu   +11 more
wiley   +1 more source

Application of dithiothreitol (DTT) assay – consistency of protocols for determination of the oxidative potential of ambient particles [PDF]

open access: yes
9th WeBIOPATR Workshop & Conference: Particulate Matter: Research and Management : Abstracts of Keynote Invited Lectures and Contributed Papers; 28th November- 1st December, 2023; Belgrade, Serbia.
Jovanović, M.   +3 more
openaire  

Adhesion‐Related Macrophages Regulate Metabolic Homeostasis Through CAV‐1 Dependency

open access: yesAdvanced Science, EarlyView.
Adipose tissue harbors a distinct macrophage subpopulation, termed adhesion‐related macrophages (ARMs), which stably adhere to adipocytes. In obesity, ARMs represent the major expanding macrophage subset. They acquire material from adipocytes and rely on Caveolin‐1 for sustained lipid handling.
Wanyu Hu   +23 more
wiley   +1 more source

Kinesin‐Induced Buckling Reveals the Limits of Microtubule Self‐Repair

open access: yesAdvanced Science, EarlyView.
This study shows that kinesin‐driven buckling induces extensive microtubule lattice damage that often exceeds intrinsic self‐repair and leads to filament failure. While curvature, motor motility, and force individually cause limited damage, their combination overwhelms repair.
Shweta Nandakumar   +9 more
wiley   +1 more source

Personalized oxidative toxicity exposure assessment: Unveiling feasibility of linking respiratory PM10 oxidative potential to human oxidative damage

open access: yesEnvironmental Chemistry and Ecotoxicology
Atmospheric particulate matter-driven oxidative stress is a crucial benchmark in evaluating health risk, yet the direct evidence linking environmental oxidability to human internal oxidative damage remains elusive.
Ying-Jie Zhang   +5 more
doaj   +1 more source

Cars2‐Mediated Cysteine Catabolism Drives Brown Fat Development and Thermogenesis Through Persulfidating EBF2

open access: yesAdvanced Science, EarlyView.
We demonstrate that Cars2, a cysteine catabolic enzyme in mouse iBAT, is critical for cold tolerance and brown adipocyte differentiation. Through its CPERS activity, Cars2 produces CysSSH/H2S to induce EBF2 persulfidation, promoting its interaction with PPARγ and BRG1 to enhance thermogenic gene expression.
Xin Peng   +8 more
wiley   +1 more source

Hamster leukemia virus: lack of endogenous DNA synthesis and unique structure of its DNA polymerase [PDF]

open access: yes, 1974
Infectious hamster leukemia virus (HaLV) contains a DNA polymerase different from those of murine and avian viruses. No endogenous reaction directed by the 60 to 70S RNA of HaLV could be demonstrated in detergenttreated HaLV virions, nor could the ...
Baltimore, David   +3 more
core  

Repeated Disuse Atrophy Imprints a Molecular Memory in Skeletal Muscle: Transcriptional Resilience in Young Adults and Susceptibility in Aged Muscle

open access: yesAdvanced Science, EarlyView.
Repeated disuse imprints a molecular memory in skeletal muscle, conferring transcriptional resilience in young adults but exaggerated susceptibility in aged muscle, driven by epigenetic regulation of aerobic metabolism, mitochondrial and NAD+ pathways.
Daniel C. Turner   +14 more
wiley   +1 more source

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