Results 181 to 190 of about 2,501,958 (326)
ABSTRACT Fragilariopsis cylindrus is a key diatom in the Southern Ocean, where low iron and manganese availability constrain primary production and biogeochemical activity. The molecular mechanisms used by polar diatoms, including F. cylindrus, to cope with trace metal limitations remain largely unexplored.
Loay J. Jabre +3 more
wiley +1 more source
Evaluation of a Particle Enhanced Turbidimetric Immunoassay (PETIA) for detecting calprotectin in sputum samples. [PDF]
Förnvik Jonsson M +5 more
europepmc +1 more source
Single‐Cell Nanodroplet Processing Proteomics Pipeline for Analysis of Human‐Derived Microglia
ABSTRACT Single‐cell omics tools provide unique insights into heterogeneous cell populations and their responses to stimuli. For example, single‐cell RNA sequencing has identified several transcriptionally distinct populations of microglia, which are resident immune cells of the central nervous system (CNS) that are responsive to CNS injury, infection,
Ashley N. Ives +7 more
wiley +1 more source
Unique response of polysulfide in serum albumin to oxidative stress. [PDF]
Ikeda-Imafuku M +11 more
europepmc +1 more source
ABSTRACT Absence of the endosomal SNAREs vti1a and vti1b results in perinatal death and severe neuronal phenotypes in mice, while lack of one of these proteins results in minor phenotypes. Proteomic differences were investigated to obtain a deeper insight into processes in which vti1a and vti1b are involved.
Julia Gottschalk +4 more
wiley +1 more source
Protocol for screening inhibitors of the fungal sphingolipid-metabolizing enzyme ceramide synthase. [PDF]
Zhong A +4 more
europepmc +1 more source
ABSTRACT It is widely established that the layers of proteins bound to the surface of nanoparticles (NPs), also known as the protein corona, critically influence their behavior in biological environments. Despite numerous proteomics studies performed in different NP‐corona systems, the impact of proteomic sample preparation methods on corona profiling ...
Asia Saorin +4 more
wiley +1 more source
Genetic and pharmacologic inhibition of calcineurin reduces biofilm formation by the pathogenic fungus Trichosporon asahii in an in vivo silkworm infection model. [PDF]
Matsumoto Y +5 more
europepmc +1 more source
ABSTRACT Triple‐negative breast cancer (TNBC) is an aggressive subtype of breast cancer characterized by high metastatic potential, poor prognosis, and limited effective therapeutic options. In this study, we investigated the molecular mechanisms underlying the anticancer effects of the nucleolin (NCL)‐targeting DNA aptamer AS1411 using label‐free ...
Ha‐Song Bae +6 more
wiley +1 more source

