CAPA neuropeptides and their receptor form an anti-diuretic hormone signalling system in the human disease vector, Aedes aegypti [PDF]
Insect CAPA neuropeptides are homologs of mammalian neuromedin U and are known to influence ion and water balance by regulating the activity of the Malpighian ‘renal’ tubules (MTs).
Ber, Lindsay Taylor+7 more
core +1 more source
A combined clinical and biomarker approach to predict diuretic response in acute heart failure [PDF]
Background: Poor diuretic response in acute heart failure is related to poor clinical outcome. The underlying mechanisms and pathophysiology behind diuretic resistance are incompletely understood.
Bloomfield, Daniel M.+16 more
core +4 more sources
Rationale and study design of intravenous loop diuretic administration in acute heart failure. DIUR-AHF [PDF]
Aims: Although loop diuretics are the most commonly used drugs in acute heart failure (AHF) treatment, their short-term and long-term effects are relatively unknown.
Di Somma, Salvatore+5 more
core +1 more source
Uji Efektivitas Diuretik Ekstrak Etanol Biji Salak (Salacca Zalacca Varietas Zalacca (Gaert.) Voss) Pada Tikus Putih Jantan Galur Wistar (Rattus Norvegicus) [PDF]
This research has purpose to examine the diuretic effects of Salak seed\u27s ethanol extract and to analyze the relationship of dose concentration of Salak seed\u27s ethanol extract upon diuretic effect on Wistar white male mice (Rattus norvegicus).
Latuconsina, N. H. (Novita)
core +3 more sources
Why do SGLT2 inhibitors reduce heart failure hospitalization? A differential volume regulation hypothesis [PDF]
The effect of a sodium glucose cotransporter 2 inhibitor (SGLT2i) in reducing heart failure hospitalization in the EMPA-REG OUTCOMES trial has raised the possibility of using these agents to treat established heart failure.
De Vecchis+22 more
core +1 more source
Medical treatment of ascites in cirrhosis [PDF]
Medical treatment of cirrhotic ascites is essentially supportive, dictated by the patient's discomfort, impaired cardiovascular or respiratory function and potential for infection. Treatment of ‘simple’ ascites (moderate fluid accumulation, serum albumin
Alexander L. Gerbes+41 more
core +1 more source
Advantages of the new loop diuretic torasemide over furosemide in patients with cirrhosis and ascites [PDF]
Torasemide is a new loop diuretic with a longer half-life and longer action than furosemide in healthy subjects. In order to evaluate the pharmacodynamic effects, single oral doses of furosemide (80 mg) and torasemide (20 mg), which were equipotent in ...
Bertheau-Reitha, Ute+4 more
core +1 more source
Serum potassium levels and outcome in acute heart failure (data from the PROTECT and COACH trials) [PDF]
Serum potassium is routinely measured at admission for acute heart failure (AHF), but information on association with clinical variables and prognosis is limited.
Bloomfield, Daniel M.+18 more
core +3 more sources
Effects of empagliflozin on cardiorespiratory fitness and significant interaction of loop diuretics [PDF]
The effects of empagliflozin on cardiorespiratory fitness in patients with type 2 diabetes mellitus (T2DM) and heart failure with reduced ejection fraction (HFrEF) are unknown.
Abbate+14 more
core +2 more sources
The synthesis of an analogue of the locust CRF-like diuretic peptide, and the biological activities of this and some C-terminal fragments. [PDF]
The synthesis is described of an analogue of the locust CRF-like diuretic peptide in which methionine in positions 1,3, and 13 is replaced by isosteric methyl-homoserine residues.
Audsley+19 more
core +1 more source