Results 41 to 50 of about 110,008 (267)

Pharmacoepidemiology of Drug Exposure in Intubated and Non-Intubated Preterm Infants With Severe Bronchopulmonary Dysplasia

Frontiers in Pharmacology, 2021
Background: Infants with severe bronchopulmonary dysplasia (BPD) are commonly treated with off-label drugs due to lack of approved therapies. To prioritize drugs for rigorous efficacy and safety testing, it is important to describe exposure patterns in ...
T. Lewis, W. Truog, L. Nelin, N. Napolitano, R. L. McKinney, and on behalf of The BPD Collaborative   +5 more
doaj   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Retraction: Diuretic effect of avocado (Persea americana Mill.) leaf extract on urine potassium and sodium levels in Sprague-Dawley rats

Current Biomedicine, 2023
Announcement of manuscript withdrawal: The author has voluntarily submitted a request for retraction of the published manuscript. Based on these considerations, the editorial board decided to permanently withdraw this manuscript from circulation, both ...
Rini Madyastuti, Nunik Nida Choerun Nisa, Ietje Wientarsih   +2 more
doaj   +1 more source

Sanggenol L Enhances Temozolomide Drug Sensitivity by Inhibiting Mitophagy and Inducing Apoptosis Through the Regulation of the TRIM16‐OPTN Axis in Glioblastoma

Advanced Science, EarlyView.
Sanggenol L, a flavonoid from mulberry, enhances glioblastoma sensitivity to temozolomide by inhibiting mitophagy and inducing apoptosis through TRIM16‐mediated OPTN degradation. In animal studies, liposomal delivery of Sanggenol L significantly improves the efficacy of its combination with TMZ, providing new insights into glioblastoma treatment ...
Hongbo Chang, Jianbing Hou, Xin Hu, Nana Hou, Minghao Xu, Yi Du, Jingyang Xu, Yongzhao Wang, Zhuohao Xie, Junbo Shi, Yundong Zhang, Hongjuan Cui   +11 more
wiley   +1 more source

IGFBP7 is a predictor of diuretic-induced acute kidney injury in the patients with acute decompensated heart failure

Türk Biyokimya Dergisi, 2022
The serum Insulin-like growth factor-binding protein 7 (IGFBP7) levels were tested to predict acute renal damage that may develop in patients with stage III–IV heart failure who were treated with intravenous diuretics in the emergency department.
Görgülü Sinan, Batur Ali, Akkaş Meltem, Dikmen Zeliha Günnur, Metin Aksu Nalan   +4 more
doaj   +1 more source

Controlling Selectivity at the First Hydrogenation Level: Synthesis of 3‐Hydroxyisoindolines by Heterogeneously Silver‐Catalyzed Monohydrogenation of Phthalimides

Advanced Science, EarlyView.
3‐Hydroxylactams are obtained from phthalimides through a heterogeneous catalyzed chemoselective hydrogenation, able to stop the process at the first hydrogenation level. By using a rationally designed [Ag/Al2O3] recyclable solid nanocatalyst, a wide range of cyclic hemiamidals are accesed through a full atom‐economical reaction that preserves (hetero ...
Carles Lluna‐Galán, Rosa Adam, Jose R. Cabrero‐Antonino   +2 more
wiley   +1 more source

Validation of Heart Failure Events in the Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) Participants Assigned to Doxazosin and Chlorthalidone

Current Controlled Trials in Cardiovascular Medicine, 2002
Background The Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) is a randomized, double-blind, active-controlled trial designed to compare the rate of coronary heart disease events in high-risk hypertensive ...
Leenen Frans HH, Williamson Jeff D, Wright Jackson T, Cushman William C, Cutler Jeffrey A, Davis Barry R, Piller Linda B, Einhorn Paula T, Randall Otelio S, Golden John S, Haywood L Julian   +10 more
doaj   +1 more source

Prognostic Value of Fractional Excretion of Urea Nitrogen at Discharge in Acute Decompensated Heart Failure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Maintaining euvolemia is crucial for improving prognosis in acute decompensated heart failure (ADHF). Although fractional excretion of urea nitrogen (FEUN) is used as a body fluid volume index in patients with acute kidney injury, the clinical
Kazutaka Nogi, Rika Kawakami, Tomoya Ueda, Maki Nogi, Satomi Ishihara, Yasuki Nakada, Yukihiro Hashimoto, Hitoshi Nakagawa, Taku Nishida, Ayako Seno, Kenji Onoue, Tsunenari Soeda, Makoto Watanabe, Yoshihiko Saito   +13 more
doaj   +1 more source

Diuretic Activity of Ethanolic Extract of Bauhinia tomentosa Linn Roots [PDF]

, 2023
Ramdas Bhat, Preeti Shanbhag, A R Shabaraya   +2 more
openalex   +1 more source

Efficacy of Sequential Hepatic Vein Embolization Following Portal Vein Embolization in Promoting Regeneration of Liver Volume and Function Before Right‐Sided Major Hepatectomy

Annals of Gastroenterological Surgery, EarlyView.
Sequential hepatic vein embolization (HVE) following portal vein embolization (PVE) significantly improves both the volume and function of the future remnant liver (FRL) compared to PVE alone. In this study, the FRL regeneration rates for volume and function were markedly higher and faster in the PVE–HVE group, with no differences in surgical outcomes ...
Thanh Tung Lai, Kosuke Matsui, Hideyuki Matsushima, Hidekazu Yamamoto, Gozo Kiguchi, Hisashi Kosaka, Van Khanh Nguyen, Yasuhiro Ueno, Shuji Kariya, Masaki Kaibori   +9 more
wiley   +1 more source