Prediction of diuretic response to tolvaptan by a simple, readily available spot urine Na/K ratio. [PDF]
BACKGROUND:Tolvaptan is vasopressin type 2 receptor antagonist that inhibits water reabsorption. It is used in combination with standard diuretics to treat ascites unresponsive to standard diuretic therapy or hyponatremia because of liver cirrhosis. This
Yasuyuki Komiyama +16 more
doaj +3 more sources
Effects of Metolazone Administration on Congestion, Diuretic Response and Renal Function in Patients with Advanced Heart Failure. [PDF]
Background: Advanced heart failure (HF) is a condition often requiring elevated doses of loop diuretics. Therefore, these patients often experience poor diuretic response. Both conditions have a detrimental impact on prognosis and hospitalization.
Palazzuoli A +9 more
europepmc +2 more sources
Background Fluid overload and venous congestion are associated with morbi-mortality in the ICU (intensive care unit). Administration of diuretics to correct the fluid balance is common, although there is no strong relationship between the consequent ...
Pierre-Grégoire Guinot +8 more
doaj +2 more sources
Renin-Angiotensin-Aldosterone System Activation and Diuretic Response in Ambulatory Patients With Heart FailurePlain-Language Summary [PDF]
Rationale & Objective: Heart failure treatment relies on loop diuretics to induce natriuresis and decongestion, but the therapy is often limited by diuretic resistance.
Jonathan G. Amatruda +6 more
doaj +2 more sources
Serum chloride and serum sodium derangements in children on prolonged furosemide therapy and their effect on diuretic response [PDF]
Background Electrolyte disturbances are not uncommon in patients on chronic furosemide therapy. We hypothesized that serum chloride (Cl) and serum sodium (Na) abnormalities may occur in children on prolonged furosemide therapy affecting the diuretic ...
Nanies Mohamed Salah EL Din Soliman +3 more
doaj +2 more sources
Evaluation of Body Position Association with Diuretic Response and Neurohormonal Activation in Patients with Acutely Decompensated Heart Failure [PDF]
Background/Objectives: Hemodynamic and neurohormonal factors, including renal perfusion and venous pressure, may affect diuretic response, which may be modulated by body position.
Mateusz Guzik, Rafał Tymków
doaj +2 more sources
Loop Diuretic Administration in Patients with Acute Heart Failure and Reduced Systolic Function: Effects of Different Intravenous Diuretic Doses and Diuretic Response Measurements. [PDF]
Background: Despite the fact that loop diuretics are a landmark in acute heart failure (AHF) treatment, few trials exist that evaluate whether the duration and timing of their administration and drug amount affect outcome.
Ruocco G +5 more
europepmc +2 more sources
Early treatment with tolvaptan improves diuretic response in acute heart failure with renal dysfunction. [PDF]
BackgroundPoor response to diuretics is associated with worse prognosis in patients with acute heart failure (AHF). We hypothesized that treatment with tolvaptan improves diuretic response in patients with AHF.MethodsWe performed a secondary analysis of ...
Matsue Y +19 more
europepmc +2 more sources
Impact of chronic kidney disease on the diuretic response of tolvaptan in acute decompensated heart failure. [PDF]
This study investigated the relationship between the initial diuretic response to tolvaptan and clinical predictors for tolvaptan responders in patients with acute decompensated heart failure (ADHF).
Ikeda S +6 more
europepmc +2 more sources
Natriuresis-guided diuretic therapy in acute heart failure: a pragmatic randomized trial
In patients with acute heart failure, personalized dosing of a diuretic led to treatment intensification in the majority of patients and improved natriuresis, but had no effects on time to all-cause mortality or heart failure rehospitalization ...
Jozine ter Maaten +2 more
exaly +2 more sources

