Results 241 to 250 of about 8,359,193 (315)

Intestinal epithelial injury and inflammation after physical work in temperate and hot environments in older men with hypertension or type 2 diabetes

Experimental Physiology, EarlyView.
Abstract We tested whether older adults with well‐controlled type 2 diabetes or hypertension, compared with age‐matched adults without chronic disease, exhibit greater intestinal damage, microbial translocation and inflammation during exertional heat stress.
Ben J. Lee, Tessa R. Flood, Sophie L. Russell, James J. McCormick, Kelli E. King, Naoto Fujii, Tatsuro Amano, Sean Notley, Glen P. Kenny   +8 more
wiley   +1 more source

The Pharmacokinetics and Pharmacodynamics of Tolvaptan in Patients with Liver Cirrhosis with Insufficient Response to Conventional Diuretics: a Multicentre, Double-blind, Parallel-group, Phase III Study

, 2012
Isao Sakaida, M. Yanase, Yoshio Kobayashi, T Yasutake, Mitsuru Okada, K Okita, Fujito Kageyama, Hiroaki Miyaoka, Hiroki Nakamura, Hiroshi Sakaeda, Kazuya Kariyama, Kenji Takaishi, Kouji Joukou, Makoto Nakamuta, Masahide Oshita, Masahiro Arai, Masaki Mita, Masaki Omoto, Mitsushige Shibatouge, Nobuyoshi Tajiri, Nobuyoshi Tanaka, Satoshi Mochida, Syotaro Sakisaka, Takafumi Ichida, Tetsuro Inokuma, Toshiaki Takayanagi, Toshiji Saibara, Toshiyuki Kimura, Tsukasa Aihara, Yoshio Tokumoto   +29 more
openalex   +1 more source

Renal afferent signaling diuretic response is impaired in streptozotocin-induced diabetic rats.

Kidney International, 2000
C. Chien, H. Chien, Y. Cheng, C. F. Chen, S. Hsu   +4 more
semanticscholar   +1 more source

Sodium–glucose cotransporter 2 inhibitors for hypertension in cardiovascular–kidney–metabolic syndrome

Experimental Physiology, EarlyView.
Abstract The antihypertensive mechanism of sodium–glucose cotransporter 2 (SGLT2) inhibitors has been traditionally attributed to osmotic diuresis. However, emerging evidence reveals multifaceted mechanisms beyond diuresis, including regulation of the renin–angiotensin–aldosterone system, sympathetic nervous system suppression, ion homeostasis ...
Chunxiang Xu, Xingyu Qiu, Nan Xu, Gensheng Zhang, Enyin Lai, Liang Zhao   +5 more
wiley   +1 more source

Urine Tubular Biomarkers Are Associated With Natriuresis in Patients With Acute Heart Failure. [PDF]

J Am Heart Assoc
Wettersten N, Duff S, Horiuchi Y, van Veldhuisen DJ, Raturi S, Estrella MM, Shlipak MG, Maisel A, Murray PT, Ix J.   +9 more
europepmc   +1 more source

Persistence of fatigue in the absence of pathophysiological mechanisms in some patients more than 2 years after the original SARS‐CoV‐2 infection

Experimental Physiology, EarlyView.
Abstract Following an acute infection with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), a substantial percentage of patients report the persistence of debilitating symptoms, often grouped in a syndrome termed ‘long COVID’. We sought to identify potential pathophysiological mechanisms responsible for the persistence, in some long COVID ...
Giovanni Baldassarre, Lucrezia Zuccarelli, Thomas Favaretto, Caterina Ursella, Andrea Palomba, Paulo Cesar do Nascimento Salvador, Emanuela Sozio, Ernesto Crisafulli, Massimo Imazio, Carlo Tascini, Bruno Grassi   +10 more
wiley   +1 more source

Loop diuretic use in patients with AKI: different severity, different response

Critical Care, 2018
Yanfei Shen, Muying Wu
doaj   +1 more source

Phytochemical Characterization of <i>Astragalus boeticus</i> L. Extracts, Diuretic Activity Assessment, and Oral Toxicity Prediction of <i>Trans</i>-Resveratrol. [PDF]

Pharmaceuticals (Basel)
Elidrissi AE, Soulo N, Elrherabi A, Chelouati T, Zwirech O, Agour A, El-Yagoubi K, Tbatou W, Nasr FA, Al-Zharani M, Qurtam AA, Derwich E.   +11 more
europepmc   +1 more source

Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications

Experimental Physiology, EarlyView.
Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó, Luis Eduardo M. Quintas   +1 more
wiley   +1 more source

Early acclimatization to high altitude: Acid–base and fluid balance dynamics during the first 2 days at 3100 m

Experimental Physiology, EarlyView.
Abstract Immediate responses to hypoxia at high altitude are hyperventilation and successive respiratory alkalosis. Alkalosis, in turn, can affect cerebrospinal fluid pH and ventilatory control. The kidneys compensate metabolically for respiratory alkalosis.
Elisabeth Skalla, Benedikt Treml, Sasa Rajsic, Michael Schreinlechner, Zoran Bukumirić, Klaus Berek, Alexander Egger, Johann Knotzer, Martin Burtscher, Axel Kleinsasser   +9 more
wiley   +1 more source