Results 41 to 50 of about 23,307 (186)

Validation of TaqMan-Based Assays for Specific Detection and Differentiation of Wild-Type and Neethling Vaccine Strains of LSDV

open access: yesMicroorganisms, 2021
Lumpy skin disease (LSD) is an important animal disease with significant health and economic impacts. It is considered a notifiable disease by the OIE. Attenuated strains of LSDV have been successfully used as vaccines (LAV) but can also produce mild or ...
Dejan Vidanović   +10 more
doaj   +1 more source

Gonadal development in scorpion mud‐turtles, Kinosternon scorpioides, in a controlled environment

open access: yesThe Anatomical Record, EarlyView.
Stage 20 was identified as the critical point for gonadal differentiation in Kinosternon scorpioides, providing key insights into sex determination. These findings enhance conservation strategies by supporting reproductive management and population viability in both in situ and ex situ programs. Abstract Research on gonadal development including sexual
Brenda Braga   +4 more
wiley   +1 more source

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

open access: yesAnimal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali   +10 more
wiley   +1 more source

Finalisation of the European Approach to Assess the Fire Performance of Facades—Brief Information on the Outcome of the Project

open access: yesFire and Materials, EarlyView.
ABSTRACT This research was conducted within the framework of project SI2.825082, funded by the European Commission—DG GROW. The project's objective was to finalise a European approach for assessing the fire performance of façades under medium and large fire exposure conditions.
Péter Tóth   +7 more
wiley   +1 more source

Single versus repeated intravenous oncolytic reovirus infusions: Implications for immune modulation and rationalised scheduling of therapy in hepatocellular carcinoma

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Oncolytic viruses are a promising immunotherapeutic approach against many malignancies. However, it is unclear whether repeated doses have improved therapeutic value or may trigger greater side effects, especially in patients with hepatocellular carcinoma whose liver is chronically damaged.
Karen J. Scott   +10 more
wiley   +1 more source

ID3 deficiency alters chromatin accessibility at DSB sites and enhances vulnerability to HDAC inhibition

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Errors in DNA double‐strand break (DSB) repair can lead to mutations, chromosomal instability, and ultimately cancer. Inhibitor of DNA‐binding 3 (ID3), a transcriptional repressor, is crucial to promoting DSB repair and helping maintain genome stability. Here, the authors investigated ID3 regulation of DNA repair via chromatin accessibility
Giuditta Della Corte   +10 more
wiley   +1 more source

Immunomodulatory and Cytotoxic Properties of Enniatin B1 in Porcine Alveolar Macrophages

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT This study investigates the immunomodulatory effects of Enniatin B1 (ENNB1), an emerging mycotoxin, on porcine alveolar macrophages (PAMs), a species‐specific model relevant to human innate immunity. PAMs were exposed to increasing ENNB1 concentrations (0.5–6 μM) over 6, 24, and 48 h.
Sara Frazzini   +4 more
wiley   +1 more source

Reduced occurrence of alpha waves during resting state predicts high attention‐deficit/hyperactivity disorder traits in young adults

open access: yesJCPP Advances, EarlyView.
Abstract Background Attention‐deficit/hyperactivity disorder (ADHD) is a neurodevelopmental condition with significant cognitive and social impacts. Identifying reliable biomarkers for ADHD is crucial for developing personalised therapies. Electroencephalography (EEG) alpha oscillations (8–12 Hz) have been suggested as a potential biomarker, but ...
Julio Rodriguez‐Larios   +2 more
wiley   +1 more source

TorchDIVA: An extensible computational model of speech production built on an open-source machine learning library.

open access: yesPLoS ONE, 2023
The DIVA model is a computational model of speech motor control that combines a simulation of the brain regions responsible for speech production with a model of the human vocal tract.
Sean P Kinahan   +2 more
doaj   +1 more source

Modern Management of the Menopause: Are We Measuring What Matters?

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective Assess uptake of the Core Outcomes in Menopause (COMMA) core outcome sets (COS) and examine whether frontline treatments for vasomotor and genitourinary symptoms have been evaluated against these key outcomes. Design Methodological review. Setting Published literature and international clinical trial registries.
Joscelyn Gan   +7 more
wiley   +1 more source

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