Results 141 to 150 of about 1,223,609 (376)

Corporate diversification and R&D intensity dynamics [PDF]

open access: yes
We study the dynamic bidirectional relationship between firm R&D intensity and corporate diversification, using longitudinal data of Spanish manufacturing companies. Our empirical approach takes into account the censored nature of the dependent variables
Cesar Alonso-Borrego   +1 more
core  

Patatin‐domain‐containing (phospho)lipases under control: Mammalian co‐regulators and pathogenic activation mechanisms

open access: yesFEBS Open Bio, EarlyView.
Patatin domain‐containing (phospho)lipases are lipid‐hydrolyzing enzymes central to metabolism, membrane remodeling, and signaling. Their activity relies on precise co‐activation mechanisms involving protein–protein interactions and conformational rearrangements.
Noopur Dubey   +2 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Ways to Increase the Efficiency of Investment Activities of Insurance Companies in Uzbekistan

open access: yesЭкономика: стратегия и практика
This article aims to develop scientific and methodological proposals and practical recommendations to improve the methodology for assessing the effectiveness of investment activities of insurance organizations.
N. M. Babaeva
doaj   +1 more source

Commodity Export Diversification in Rwanda - Many Export Discoveries with Little Scaling-Up [PDF]

open access: yes
Increased diversification of commodity exports, and increased numbers of high-value commodity exports, are needed to generate employment and meet the Government of Rwanda´s targets for poverty reduction.
Chandra, Vandana   +2 more
core   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

open access: yesAging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Towards conservation and sustainable use of an indigenous crop: A large partnership network enabled the genetic diversity assessment of 1539 fonio (Digitaria exilis) accessions

open access: yesPlants, People, Planet
Social Impact Statement The use of neglected and underutilized species (NUS) in agrosystems is a potential solution to the challenges arising from global change.
Thomas Kaczmarek   +42 more
doaj   +1 more source

Home - About - Disclaimer - Privacy