Results 61 to 70 of about 29,442 (291)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Diversifying the Team [PDF]

open access: yesAmerican Journal of Pharmaceutical Education, 2008
How do you define diversity in the departmental or team environment? This question was posed to attendees of a pharmacy practice department heads roundtable session at the American Association of Colleges of Pharmacy (AACP) 2007 Annual Meeting. Most of the responses fit into 1 of 3 categories: * "Usually based on ethnicity/race. Also considers gender."
openaire   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

How Cichlids Diversify

open access: yesScience, 2012
The extreme diversity of cichlid fishes in East Africa helps to elucidate how and why organisms diversify.
Santos, M. E., Salzburger, W.
openaire   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Gold versus stock investment: An econometric analysis [PDF]

open access: yesInternational Journal of Development and Sustainability, 2012
It is important to have a portfolio in investment to diversify the investment to different kinds of instruments. Based on previous research, it is concluded that gold is a good portfolio diversifier, a hedge against stock and safe haven in extreme stock ...
Martin Surya Mulyadi, Yunita Anwar
doaj  

Four Freedoms, For All: American Information Agencies and the Effort to Publicize Nazi Crimes against Humanity

open access: yesRevue LISA, 2012
En juin 1942, le Président Franklin Delano Roosevelt a créé le bureau de l’information de guerre dont la mission consistait à « rendre plus accessible et intelligible l’effort de guerre américain, les politiques gouvernementales, la progression des ...
Jeffrey Demsky
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

International Evidence on Real Estate as a Portfolio Diversifier [PDF]

open access: yes
This paper provides an international comparison of the benefits of including real estate assets – both domestic and international – in mixed-asset portfolios.
Jon Lekander   +2 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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