EukRibo: a manually curated eukaryotic 18S rDNA reference database to facilitate identification of new diversity [PDF]
Cédric Berney +4 more
openalex +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Examining the Link Between Diversity and Firm Performance: The Effects of Diversity Reputation and Leader Racial Diversity [PDF]
Given the scarcity of empirical research on the impact of diversity on organizational performance, we used longitudinal data for 100 firms to test hypotheses related to the effects of diversity reputation and leader racial diversity on firm financial ...
Park, Hyeon Jeong +1 more
core +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Changes in soil microbial substrate utilization in response to altered litter diversity and precipitation in a Mediterranean shrubland [PDF]
Ammar Shihan +5 more
openalex +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Tris(2-chloroethyl) phosphate (TCEP) and tris(2-chloro-1-methylethyl) phosphate (TCPP) are increasingly co-detected in various aquatic environments, yet their combined toxicity remains poorly understood.
Xin-Dan Cao +6 more
doaj +1 more source
Microbial functional diversity in rhizosphere and non-rhizosphere soil of different dominant species in a vegetation concrete slope [PDF]
Lu Xia +5 more
openalex +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Cleavage of Bcl-2-associated athanogene by metacaspase determines plant antiviral immunity
Nucleotide-binding leucine-rich repeat receptors (NLRs) function as core components of innate immunity in both plants and animals. In animals, NLR activation initiates caspase-mediated immune signaling.
Lin Liang +9 more
doaj +1 more source

