Results 131 to 140 of about 5,990,883 (357)
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Nationalism in Latin America. Diversity and Unity [PDF]
, 1967 John J. Johnson
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Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
Unitary Space Time Constellation Analysis: An Upper Bound for the Diversity [PDF]
, 2003 The diversity product and the diversity sum are two very important parameters for a good-performing unitary space time constellation. A basic question is what the maximal diversity product (or sum) is.
Han, Guangyue, Rosenthal, Joachim
core +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
The Diversity of the Insect Fauna in a Hedgerow and Neighbouring Fields [PDF]
, 1969 Theodore Lewis
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The Relationship Between Diversity and Performance in Major League Baseball Teams: Conflict\u27s Mediating Effect [PDF]
, 2011 Diversity in the workplace is a growing reality around the world as the globalizing economy has prompted the growth of work teams comprised of individuals from diverse backgrounds with different values, experiences, knowledge, and skills.
Campion, Michelle Maureen
core +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source