Results 201 to 210 of about 1,455,942 (268)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Host-Associated Bacterial Community Changes After Laboratory Introduction Vary With Wolbachia Presence. [PDF]

Environ Microbiol
Brinker P, Salles JF, Beukeboom LW, Fontaine MC.   +3 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Nitrogen addition has negative effects on bacterial diversity and stability, but simulated grazing mitigates these effects. [PDF]

Front Microbiol
Liu Z, Dong Y, Jiang A, Sun Z, Wu Y, Lei Y, Shan X, Wu K.   +7 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Whole-genome simple sequence repeat development and genetic diversity analysis of sponge gourd (<i>Luffa cylindrica</i>). [PDF]

PeerJ
Cui R, Wang Z, Jia L, Miao Y, Yan C, Qian M, Shu Y, Zhang K.   +7 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Microbiome signatures of mangroves and salt marsh halophyte rhizosphere soil sediments: a metagenomic approach. [PDF]

Sci Rep
Sujeeth NK, Dharani Bommi KB, Manojkumar S, Angayarkanni J, Gnanadesigan M.   +4 more
europepmc   +1 more source

Oral microbiome diversity shapes the association between leisure-time physical activity and cognitive function among older adults. [PDF]

iScience
You Y, Cui Y, Zheng K, Yang H, Yu C, Wang Q, Chen Y, Ma X.   +7 more
europepmc   +1 more source

T-cell receptor gamma (TRG) diversity predicts peripheral blood involvement in primary cutaneous T-cell lymphoma. [PDF]

Blood Neoplasia
Ramesh R, Colbourn R, Van Deerlin VM, Halper-Stromberg E.   +3 more
europepmc   +1 more source