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Diversity & Inclusion Update - Spring 2019
, 2019 The Spring 2019 newsletter discusses ongoing campus initiatives to facilitate diversity and inclusion efforts on campus. Topics discussed include: The First Generation Campaign; the growth of Latinx house; faculty training around diversity and inclusion ...
Office of Diversity & Inclusion,
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
, 2006 Presents findings from a survey that examines why nonprofit executives leave their jobs. Offers recommendations for strengthening and supporting current leadership, creating more diversity, and developing the next generation of nonprofit ...
Jeanne Bell +2 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
NP2020: Issues and Answers from the Next Generation [PDF]
, 2008 A report of a three-day conference on nonprofit leadership, held in Grand Rapids, MI in July 2007, identified that there is a leadership deficit, mentoring is needed for emerging leaders, structural challenges create barriers to nonprofit careers, and ...
Dorothy A. Johnson Center for Philanthropy
core +2 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
DG2GAN: improving defect recognition performance with generated defect image sample
Scientific ReportsThis article aims to improve the deep-learning-based surface defect recognition. In actual manufacturing processes, there are issues such as data imbalance, insufficient diversity, and poor quality of augmented data in the collected image data for ...
Fuqin Deng +7 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Social SciencesThe Windrush Generation (WG) and their descendants continue to experience adversity in the UK, including racism and the Windrush Scandal, with such adversities absent from psychological research literature.
Jessica Blumsom +6 more
doaj +1 more source