Results 41 to 50 of about 72,496 (213)

Diverticulosis today: unfashionable and still under-researched

Therapeutic Advances in Gastroenterology, 2016
Diverticulosis of the colon is a widespread disease, and its prevalence is increasing especially in the developing world. The underlying pathological mechanisms that cause the formation of colonic diverticula remain unclear but are likely to be the ...
Antonio Tursi
doaj   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

Acute left-sided colonic diverticulitis: clinical expressions, therapeutic insights, and role of computed tomography [PDF]

, 2016
Patrick Ambrosetti Department of Surgery, Clinique Générale Beaulieu, Geneva, Switzerland Abstract: The diagnostic approach of patients with suspected acute diverticulitis remains debated.
Ambrosetti P
core  

The relationship between colonic diverticulosis and abdominal visceral and subcutaneous fat accumulation measured by abdominal CT scan

The Turkish Journal of Gastroenterology, 2014
Background/Aims: Besides age, risk factors for colonic diverticular disease include dietary meat intake and Western lifestyles, which are also risk factors for obesity.
Sang Pyo Lee, Yong Woo Ahn, Oh Young Lee, Kang Nyeong Lee   +3 more
doaj   +1 more source

Safety and pharmacokinetics of anumigilimab for hidradenitis suppurativa or palmoplantar pustulosis: A phase 1b study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Anumigilimab, a novel anti‐G‐CSF receptor antibody, was investigated in a phase 1b trial involving 39 patients with hidradenitis suppurativa or palmoplantar pustulosis. No serious safety concerns related to anumigilimab were noted, and PK and PD were dose dependent.
Johannes S. Kern, Simon Francis Thomsen, Georgios Kokolakis, Maurizio Podda, Gregor B. E. Jemec, Kurt Gebauer, Claus Zachariae, John Frew, Pablo Fernandez‐Peñas, Falk G. Bechara, Stefan Beissert, Sourabh Malandkar, Karen Scalzo‐Inguanti, Partha Nandy, Selvakumar Sukumar   +14 more
wiley   +1 more source

Endoscopic Visualization of a Jejuno‐Colonic Fistula in a Case of Monomorphic Epitheliotropic Intestinal T‐Cell Lymphoma

DEN Open, Volume 7, Issue 1, April 2027.
Monomorphic epitheliotropic intestinal T‐cell lymphoma (MEITL) rarely presents with gastrointestinal fistula formation. A rare case of MEITL is identified in an elderly woman with marked weight loss and hypoalbuminemia, in whom a jejunocolic fistula is directly visualized endoscopically.
Kanami Ota, Yuichi Matsuno, Yoshiaki Taniguchi, Noriyuki Imazu, Shinichiro Kawatoko, Yutaro Ihara, Tomohiro Nagasue, Keisuke Kawasaki, Tomohiko Moriyama, Junji Umeno   +9 more
wiley   +1 more source

Colon Single Stripe Sign in Chronic NSAID Use During Norovirus Infection: A Two‐Hit Model of Ischemic Colitis

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT The colon single stripe sign (CSSS) is associated with ischemic‐pattern colonic injury. We report a 69‐year‐old woman with norovirus infection, hematochezia, recurrent left‐sided colitis, and chronic NSAID use found to have CSSS on colonoscopy, suggesting a multifactorial “two‐hit” mechanism involving NSAID‐related mucosal vulnerability and ...
Sushrut Ingawale, Rahul Kothari, Pujitha Vallivedu, Shivaji Karki, Gagandeep Singh Talwar, Jack Jacob, David Regelmann, Prabin Sharma   +7 more
wiley   +1 more source

Computed tomography in acute left colonic diverticulitis.

, 1997
BACKGROUND The use of computed tomography (CT) in acute left colonic diverticulitis remains controversial. The purpose of this study was to define the value of CT both during the acute phase of inflammation and, later, to indicate secondary complications
Ambrosetti P, Morel P, Terrier F, Becker C, Grossholz M   +4 more
core   +1 more source

Giant Colonic Diverticulitis, an Extremely Rare Presentation of a Rare Disease — Clinical Presentation and Literature Review

Journal of Coloproctology, 2022
Introduction Giant colonic diverticulum (GCD) is rare phenomenon, with less than 200 cases described in the literature. One of the complications of GCD is diverticulitis.
Eliahu Y. Bekhor, Ran Orgad, Hila Shmilovitch, Rotem Ayalon, Oleg Kaminsky   +4 more
doaj   +1 more source

Global Prevalence of Self‐Reported Alarm Features in the General Population and Among Individuals With Disorders of Gut–Brain Interaction—Results From the Rome Foundation Global Epidemiology Study

United European Gastroenterology Journal, Volume 14, Issue 7, September 2026.
ABSTRACT Background Data on the global prevalence of alarm features in the general population and among individuals with disorders of gut–brain interaction (DGBI) are limited. Methods We analysed data from the Rome Foundation Global Epidemiology Study to estimate the prevalence of fourteen self‐reported alarm features in the global population and among
Jessica Sjölund, Jóhann P. Hreinsson, Brian E. Lacy, Hans Törnblom, Shrikant I. Bangdiwala, Olafur S. Palsson, Ami D. Sperber, Magnus Simren   +7 more
wiley   +1 more source