Results 51 to 60 of about 35,421 (212)

A Feasibility Study of the Repurposing of Prazosin to Improve Treatment Outcomes in Men Receiving Radiotherapy for Prostate Cancer (MiniRaP‐00)

The Prostate, EarlyView.
ABSTRACT Background Further work is needed to improve treatment outcomes for prostate cancer (PCa), with the repurposing of the α1‐adrenoreceptor antagonists presenting a potential solution. This feasibility clinical trial presents the first prospective data of the use of an α1‐adrenoreceptor antagonist in men undergoing radiotherapy for PCa.
Liam D. King, David Christie, Daniel Cehic, Wendy Dare, Russ Chess‐Williams, Donna Sellers, Catherine McDermott, Alexandra McCarthy, Shailendra Anoopkumar‐Dukie   +8 more
wiley   +1 more source

Increasing trend in admission rates and costs for acute diverticulitis during 2005–2015: real-life data from the Abruzzo Region

Therapeutic Advances in Gastroenterology, 2018
Background: Scarce data are available on the epidemiological trend of diverticulitis and its financial burden in Italy. The aim of this work was to explore a potential variation in the rate and costs of hospital admissions for uncomplicated and ...
Simona Cammarota, Martina Cargiolli, Paolo Andreozzi, Bernardo Toraldo, Anna Citarella, Maria Elena Flacco, Gian Andrea Binda, Bruno Annibale, Lamberto Manzoli, Rosario Cuomo   +9 more
doaj   +1 more source

Essential updates 2018/2019: Colorectal (benign)

Annals of Gastroenterological Surgery, 2020
This review outlines current topics on the surgical treatment of benign colorectal diseases, with a focus on inflammatory bowel disease (IBD) and diverticulitis.
Takayuki Ogino, Tsunekazu Mizushima, Chu Matsuda, Masaki Mori, Yuichiro Doki   +4 more
doaj   +1 more source

Beyond Immunosuppression: Defining Perioperative Risk in Transplant Patients Undergoing Colorectal and Small Bowel Surgery

World Journal of Surgery, EarlyView.
Colorectal and small bowel surgery in transplant (TX) recipients presents unique perioperative challenges due to immunosuppression and comorbidities, with poorly defined risks. ABSTRACT Background Colorectal and small bowel surgery in transplant (TX) recipients presents unique perioperative challenges due to immunosuppression and comorbidities, with ...
Phil Meister, Samira Vestweber, Jan Neuhaus, Marc A. Reschke, Ulf Neumann, Andreas D. Rink   +5 more
wiley   +1 more source

Identification of core gene-gut microbiome associations in diverticulitis patients through a two-sample mendelian randomization and bioinformatics-based investigation

Global Medical Genetics
Background: Previous studies have suggested a potential link between the gut microbiota and diverticulitis. However, the causal relationships as well as underlying mechanisms remain unclear. Methods: The causal effects of gut microbiota on diverticulosis
Wende Hao, Zhenjun Wang, Huachong Ma
doaj   +1 more source

Epiploic Appendagitis Mimicking Recurrent Diverticulitis

Case Reports in Surgery, 2018
Here, we report a case in which a patient with an extensive history of diverticulitis of the sigmoid colon presented with left lower quadrant abdominal pain similar to her previous episodes of diverticulitis.
R. Plummer, Y. Sekigami, Lilian Chen, James Yoo   +3 more
doaj   +1 more source

Smoking Is Associated with an Increased Risk for Surgery in Diverticulitis: A Case Control Study. [PDF]

PLoS ONE, 2016
Cigarette smoking increases the risk of surgery in Crohn's disease. However, the effect of smoking on the need for surgery for diverticulitis is unknown.We evaluated whether smoking was a risk factor for surgery among patients admitted to hospital with ...
Michael J Diamant, Samuel Schaffer, Stephanie Coward, M Ellen Kuenzig, James Hubbard, Bertus Eksteen, Steven Heitman, Remo Panaccione, Subrata Ghosh, Gilaad G Kaplan   +9 more
doaj   +1 more source

Complete mesocolic excision does not increase short-term complications in laparoscopic left-sided colectomies : a comparative retrospective single-center study [PDF]

, 2019
Background: Since the implementation of total mesorectal excision (TME) in rectal cancer surgery, oncological outcomes improved dramatically. With the technique of complete mesocolic excision (CME) with central vascular ligation (CVL), the same surgical ...
Claeys, Donald, Defoort, Barbara, Dewulf, Maxime, Kalmar, Alain, Muysoms, Filip, Pletinckx, Pieter, Vandenberk, Bert   +6 more
core   +2 more sources

Slow Transit Constipation: Pathophysiological Perspectives and Management Updates

Journal of Digestive Diseases, EarlyView.
Slow transit constipation (STC) is a complex neuromuscular disorder driven by interstitial cells of Cajal (ICCs) loss and enteric neuropathy. Diagnosis relies on objective transit testing while excluding pelvic floor dysfunction. Management follows a stepwise, phenotype‐driven approach, progressing from conventional laxatives to emerging targeted ...
Athanasios Syllaios, Stavros P. Papadakos, Alexandros Ioannou, Maximos Frountzas, Dimosthenis Michelakis, Dimitrios Patsouras, Spyridon Dritsas, Manousos‐Georgios Pramateftakis, Dimitrios Schizas   +8 more
wiley   +1 more source

Predictive score for diagnosing acute colonic diverticulitis in the emergency department: a retrospective study

BMC Emergency Medicine
Background Acute diverticulitis is commonly misdiagnosed among patients with acute abdominal pain in the emergency department (ED). There are predictive scores that assist in the diagnosis of acute left-sided diverticulitis, but no scoring system is ...
Siriwimon Tantarattanapong, Choasita Glawsongkram, Wasuntaraporn Pethyabarn   +2 more
doaj   +1 more source