Results 71 to 80 of about 57,888 (323)

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman   +3 more
wiley   +1 more source

Essential updates 2018/2019: Colorectal (benign)

open access: yesAnnals of Gastroenterological Surgery, 2020
This review outlines current topics on the surgical treatment of benign colorectal diseases, with a focus on inflammatory bowel disease (IBD) and diverticulitis.
Takayuki Ogino   +4 more
doaj   +1 more source

Elective Surgery for Diverticulitis in Swiss Hospitals

open access: yesFrontiers in Surgery, 2021
Objective: To assess current management of diverticulitis in Switzerland.Methods: Prospective observational study of diverticulitis management and outcomes in surgical departments over a 3-month time period.
Seraina Faes   +176 more
doaj   +1 more source

A 52‐week open‐label extension study to evaluate the safety and efficacy of oral rimegepant for the preventive treatment of migraine

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To assess the safety, tolerability, and treatment effects of rimegepant 75 mg every other calendar day (EOD) for the preventive treatment of migraine in a 52‐week, open‐label extension (OLE) study. Background Rimegepant is an oral small molecule calcitonin gene–related peptide receptor antagonist approved for the acute treatment of ...
David Kudrow   +3 more
wiley   +1 more source

Increasing trend in admission rates and costs for acute diverticulitis during 2005–2015: real-life data from the Abruzzo Region

open access: yesTherapeutic Advances in Gastroenterology, 2018
Background: Scarce data are available on the epidemiological trend of diverticulitis and its financial burden in Italy. The aim of this work was to explore a potential variation in the rate and costs of hospital admissions for uncomplicated and ...
Simona Cammarota   +9 more
doaj   +1 more source

Safety and efficacy of nemolizumab for atopic dermatitis up to 2 years in open‐label extension study

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
This study evaluated long‐term safety and efficacy in patients with moderate‐to‐severe atopic dermatitis. Patients with and without previous nemolizumab experience received nemolizumab 30 mg Q4W plus TCS/TCI. Nemolizumab was well‐tolerated through 104 weeks with clinically meaningful improvements in disease signs and symptoms.
Matthias Augustin   +24 more
wiley   +1 more source

Identification of core gene-gut microbiome associations in diverticulitis patients through a two-sample mendelian randomization and bioinformatics-based investigation

open access: yesGlobal Medical Genetics
Background: Previous studies have suggested a potential link between the gut microbiota and diverticulitis. However, the causal relationships as well as underlying mechanisms remain unclear. Methods: The causal effects of gut microbiota on diverticulosis
Wende Hao, Zhenjun Wang, Huachong Ma
doaj   +1 more source

Epiploic Appendagitis Mimicking Recurrent Diverticulitis

open access: yesCase Reports in Surgery, 2018
Here, we report a case in which a patient with an extensive history of diverticulitis of the sigmoid colon presented with left lower quadrant abdominal pain similar to her previous episodes of diverticulitis.
R. Plummer   +3 more
doaj   +1 more source

Smoking Is Associated with an Increased Risk for Surgery in Diverticulitis: A Case Control Study. [PDF]

open access: yesPLoS ONE, 2016
Cigarette smoking increases the risk of surgery in Crohn's disease. However, the effect of smoking on the need for surgery for diverticulitis is unknown.We evaluated whether smoking was a risk factor for surgery among patients admitted to hospital with ...
Michael J Diamant   +9 more
doaj   +1 more source

Validation of the PROMIS Global Physical and Mental Health Scale for Gastrointestinal Disorders: A Large‐Scale Cross‐Sectional Survey

open access: yesNeurogastroenterology &Motility, EarlyView.
The 4‐item revised version of the Hays model from the PROMIS Global Health Scale exhibits stronger psychometric properties than the original model. This ultra‐brief assessment tool is a reliable measure for evaluating quality of life in both gastrointestinal and non‐gastrointestinal cohorts.
Pragalathan Apputhurai   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy