Results 141 to 150 of about 105,757,333 (286)

Optimal Minimax Rate of Smoothing Parameter in Distributed Nonparametric Specification Test

open access: yesAxioms
A model specification test is a statistical procedure used to assess whether a given statistical model accurately represents the underlying data-generating process. The smoothing-based nonparametric specification test is widely used due to its efficiency
Peili Liu   +3 more
doaj   +1 more source

Divide and conquer [PDF]

open access: yesNature Reviews Microbiology, 2019
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Parallelizing divide-and-conquer algorithms - Microtasking versus autotasking

open access: yes, 1990
Algorithms based on a divide-and-conquer strategy are well qualified for being implemented in a multitasking environment. The idea of the divide-and-conquer paradigm is to fragment a problem into subproblems of the same kind, to solve the subproblems ...
Renate Knecht, Knecht, Renate
core   +1 more source

Correlation clustering: divide and conquer

open access: yesAnnals of computer science and information systems, 2016
László Aszalós, Mária Bakó
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Parallel combinator reduction : some performance bounds [PDF]

open access: yes
A parallel graph reduction machine simulator is described. This performs combinator reduction and can simulate various different parallel reduction strategies. A number of functional programs are examined, and experimental results presented comparing the
Joy, Mike, Axford, Tom
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Home - About - Disclaimer - Privacy