Results 191 to 200 of about 105,757,333 (286)

Divide and Conquer: A Simple, Modern Technique for Collaborative Small Group Learning with Reciprocal Peer Teaching. [PDF]

J Microbiol Biol Educ, 2021
Samsa LA, Goller CC.
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Divide and conquer approach for genome-wide association studies. [PDF]

Genetics
Özkaraca Mİ, Agung M, Navarro P, Tenesa A.   +3 more
europepmc   +1 more source

Unscented Particle Filter Algorithm Based on Divide-and-Conquer Sampling for Target Tracking. [PDF]

Sensors (Basel), 2021
Du S, Deng Q.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Parallel implementation of divide-and-conquer semiempirical quantum chemistry calculations

, 1998
We have implemented a parallel divide-and-conquer method for semiempirical quantum mechanical calculations. The standard message passing library, the message passing interface (MPI), was used. In this parallel version, the memory needed to store the Fock
Pan, W., Yang, WT, Lee, TS
core  

A divide-and-conquer approach to uncover the genomic structure of the highly virulent RA strain of Trypanosoma cruzi. [PDF]

Sci Rep
Balouz V, Cepeda Dean AA, Romer G, Robello C, Berná L, Buscaglia CA.   +5 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Divide and Conquer In Reliability Analyses

, 2009
All product is not created equal. Some units are more likely to fail in service than others. Thus, in reliability evaluations, you need to identify subpopulations with different failure susceptibility.
Doganaksoy, Necip, Hahn, Gerald, Meeker, William   +2 more
core  

Divide and Conquer-Targeted Therapy for Triple-Negative Breast Cancer. [PDF]

Int J Mol Sci
Nedeljković M, Vuletić A, Mirjačić Martinović K.   +2 more
europepmc   +1 more source