Results 241 to 250 of about 105,757,333 (286)
A Divide and Conquer Strategy against the Covid-19 Pandemic?!
, 2020 Mangat P.
europepmc +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
Characterizing and defending against divide-conquer-scanning worms
Computer Networks, 2010 Internet worms are a significant security threat. Divide-conquer scanning is a simple yet effective technique that can potentially be exploited for future Internet epidemics.
Zesheng Chen
exaly +1 more source
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Scientific American, 2015
The article discusses research by David Matus of Stony Brook University and David Sherwood of Duke University, to study the ability of cancer cells to invade other tissues conducted using Caenorhabditis elegans as a metastasis model organism.
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The article discusses research by David Matus of Stony Brook University and David Sherwood of Duke University, to study the ability of cancer cells to invade other tissues conducted using Caenorhabditis elegans as a metastasis model organism.
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Science, 2017
Dendritic Cells Dendritic cells (DCs) play a crucial role in priming T cell–driven antiviral responses. Silvin et al. examined the paradox of how virus-infected DCs retain the ability to drive adaptive immune responses. In response to endocytic viruses, they found CD1c+ DCs to be susceptible to infection and death, whereas CD141+ DCs were not.
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Dendritic Cells Dendritic cells (DCs) play a crucial role in priming T cell–driven antiviral responses. Silvin et al. examined the paradox of how virus-infected DCs retain the ability to drive adaptive immune responses. In response to endocytic viruses, they found CD1c+ DCs to be susceptible to infection and death, whereas CD141+ DCs were not.
openaire +2 more sources
Proceedings of the Genetic and Evolutionary Computation Conference, 2018
Neuroevolution is a powerful and general technique for evolving the structure and weights of artificial neural networks. Though neuroevolutionary approaches such as NeuroEvolution of Augmenting Topologies (NEAT) have been successfully applied to various problems including classification, regression, and reinforcement learning problems, little work has ...
Tyler McDonnell +8 more
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Neuroevolution is a powerful and general technique for evolving the structure and weights of artificial neural networks. Though neuroevolutionary approaches such as NeuroEvolution of Augmenting Topologies (NEAT) have been successfully applied to various problems including classification, regression, and reinforcement learning problems, little work has ...
Tyler McDonnell +8 more
openaire +2 more sources