Results 121 to 130 of about 10,260 (285)

Divide and Conquer

open access: yes, 2007
This chapter considers instances in which widening the political base for reform may still be desirable, but is practically unfeasible. This scenario typically emerges when the benefits from reform are dispersed among many economic agents, postponed to ...
Tsyganok, Lidia   +11 more
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

A Theory of Buyer Fragmentation: Divide-and-Conquer Intensifies Competition [PDF]

open access: yes, 2014
It is well-known from Innes and Sexton (1993, 1994) that divide-and-conquer contracts allow an incumbent facing a potential entrant to extract more surplus from buyers and hence buyers suffer from the strategy.
Menicucci, Domenico, Jeon, Doh-Shin
core  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

A strategy to classify and resolve ambiguities when reverse engineering drawings to CAD models

open access: yesCogent Engineering
Oftentimes, designers need to reverse engineer detailed design drawings to create 3D models. These drawings are commonly accepted as complete information sources in design datasets but may contain errors or ambiguities and lead to misinterpretation ...
Pedro Company   +4 more
doaj   +1 more source

Implementation of divide-and-conquer algorithms on multiprocessors

open access: yes, 1991
Algorithms with a divide-and-conquer structure are suitable candidates for parallelization. The idea of the divide-and-conquer paradigm is to fragment a problem into subproblems of the same kind, to solve the subproblems recursively, and, finally, to ...
Renate Knecht   +2 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Adaptive multi-threshold image segmentation algorithm

open access: yesTongxin xuebao
Aiming at the issues that most existing multi-threshold segmentation methods struggle to accurately locate the optimal threshold combination and face soaring computational complexity with more thresholds, an adaptive multi-threshold image segmentation ...
LONG Jianwu, LI Jihao, ZENG Shuifei
doaj  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

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