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From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

HAlign-G: rapid and low-memory multiple-genome aligner for large-scale closely related genomes. [PDF]

open access: yesGenome Biol
Zhang P   +8 more
europepmc   +1 more source
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Quantile Regression in Big Data: A Divide and Conquer Based Strategy

Computational Statistics and Data Analysis, 2020
Quantile regression, which analyzes the conditional distribution of outcomes given a set of covariates, has been widely used in many fields. However, the volume and velocity of big data make the estimation of quantile regression model extremely difficult
Yong Zhou
exaly   +2 more sources

Quantum K-Nearest Neighbor Classification Algorithm via a Divide-and-Conquer Strategy

Advanced Quantum Technologies
The K‐nearest neighbor algorithm is one of the most frequently applied supervised machine learning algorithms. Similarity computing is considered to be the most crucial and time‐consuming step among the classical K‐nearest neighbor algorithm. A quantum K‐
Li-Hua Gong, Nan-Run Zhou
exaly   +2 more sources

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