Results 21 to 30 of about 30,320 (133)
, 2016 High-level abstractions for parallel programming are still immature. Computations on complicated data structures such as pointer structures are considered as irregular algorithms.
Shigeyuki Sato, 佐藤 重幸
core +2 more sources
Radix-2 x 2 x 2 algorithm for the 3-D discrete hartley transform [PDF]
, 2001 The discrete Hartley transform (DHT) has proved to be a valuable tool in digital signal/image processing and communications and has also attracted research interests in many multidimensional applications.
Alshibami, O.H. +2 more
core +1 more source
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
Molecular Oncology, EarlyView.We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas +15 more
wiley +1 more source
On the quantum time complexity of divide and conquer
, 2023 We initiate a systematic study of the time complexity of quantum divide and conquer algorithms for classical problems. We establish generic conditions under which search and minimization problems with classical divide and conquer algorithms are amenable ...
Allcock, Jonathan +4 more
core
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
Molecular Oncology, EarlyView.The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song +13 more
wiley +1 more source
Deriving divide-and-conquer dynamic programming algorithms using solver-aided transformations [PDF]
, 2016 We introduce a framework allowing domain experts to manipulate computational terms in the interest of deriving better, more efficient implementations.It employs deductive reasoning to generate provably correct efficient implementations from a very high ...
Chowdhury, Rezaul +6 more
core +1 more source
Molecular Oncology, EarlyView.TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam +9 more
wiley +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source
Quantum Computing and a Unified Approach to Fast Unitary Transforms
, 2002 A quantum computer directly manipulates information stored in the state of quantum mechanical systems. The available operations have many attractive features but also underly severe restrictions, which complicate the design of quantum algorithms.
Agaian, Sos S., Klappenecker, Andreas
core +1 more source
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source