Results 81 to 90 of about 36,225 (338)
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
The design of divide and conquer algorithms
Science of Computer Programming, 1985 The structure common to a class of divide and conquer algorithms is represented by a program scheme. A theorem is presented which relates the functionality of a divide and conquer algorithm to its structure and the functionalities of its subalgorithms.
openaire +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
A Comparison of Approximation Algorithms for the MaxCut-Problem [PDF]
, 2001 In this paper we compare, from a practical point of view, approximation algorithms for the problem MaxCut . For this problem, we are given an undirected graph G = (V;E) with vertex set V and edge set E, and we are looking for a partition V = V1 [ V2 with
Dolezal, Oliver +2 more
core
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Large-scale wireless coverage optimization: A quantum approach
ICT ExpressWireless network coverage optimization is critical for improving service quality. However, optimizing large-scale networks remains challenging for both classical algorithms and quantum methods in the NISQ era.
Chengkang Pan +7 more
doaj +1 more source
A Divide-and-Conquer Bat Algorithm with Direction of Mean Best Position for Optimization of Cutting Parameters in CNC Turnings [PDF]
, 2022 Xingwang Huang +3 more
openalex +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
A non-commutative algorithm for multiplying (7 $\times$ 7) matrices using 250 multiplications
, 2017 We present a non-commutative algorithm for multiplying (7x7) matrices using 250 multiplications and a non-commutative algorithm for multiplying (9x9) matrices using 520 multiplications.
Sedoglavic, Alexandre
core
Accelerating Metropolis-Hastings algorithms: Delayed acceptance with prefetching [PDF]
, 2014 MCMC algorithms such as Metropolis-Hastings algorithms are slowed down by the computation of complex target distributions as exemplified by huge datasets. We offer in this paper an approach to reduce the computational costs of such algorithms by a simple
Banterle, Marco +2 more
core +1 more source