Results 161 to 170 of about 4,897,555 (276)

The importance of crash reporting requirements and how they affect analyses of factors associated with wildlife-vehicle collisions. [PDF]

PLoS One
Jørgensen AV, Cramer PC, Mack WM, Ellis-Felege SN.   +3 more
europepmc   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Divided attention and manual visuomotor control in stroke: a combined dual-task and eye movement study. [PDF]

J Neuroeng Rehabil
Dziezuk E, Le Boterff Q, Van Ravestyn C, Mairesse S, Hamdoun S, Calvet D, Daghsen L, Carment L, Rosso C, Maier MA, Turc G, Mas JL, G Lindberg P.   +12 more
europepmc   +1 more source

On the approximation of derivatives using divided difference operators preserving the local convergence order of iterative methods

, 2012
Miquel Grau-Sánchez, Miquel Noguera, Sergio Amat   +2 more
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Assessing the attentional demand: improvements to the experimental protocol and possible learning effects. [PDF]

Front Psychol
Di Pompeo I, Marcaccio M, Migliore S, Curcio G.   +3 more
europepmc   +1 more source

The Difference in the Serum Levels of BDNF, IL-6, IL-8, IL-10 and EGF in Oncology Patients Divided According to the Presence of Symptoms of Depression

, 2012
L Holubec, Ondřej Fiala, Vít Martin Matějka, Jiří Podlipný, Jana Dreslerova, Jindra Vrzalová, Ondřej Topolčan, Jindřich Fínek, Tomáš Svoboda   +8 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Retinal vessel density alteration after FS-LASIK for myopia with different axial lengths. [PDF]

Int J Ophthalmol
Fu CY, Zheng Y, Zhai CB, Huang HB, Chen X, Dong YR, Hu YB, Xu W, Liu J, Huang Y, Sun N, Chen XY.   +11 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source