Results 181 to 190 of about 15,511,573 (358)

Confluent Vandermonde matrices, divided differences, and\n Lagrange-Hermite interpolation over quaternions [PDF]

, 2015
Vladimir Bolotnikov
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Volume Measurements of the Knee Articular Cartilage and Epiphyseal Bone for Evaluating the Structural Characteristics of the Discoid Lateral Meniscus. [PDF]

Cureus
Nagawa K, Hara Y, Kakemoto S, Shimizu H, Tsuchihashi S, Sugita N, Inoue K, Kozawa E.   +7 more
europepmc   +1 more source

The Cauchy double alternant and divided differences

, 2006
Wenchang Chu
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Effects of a Sodium-Glucose Cotransporter 2 Inhibitor Dapagliflozin on Pancreas in Obese Diabetic Mice. [PDF]

In Vivo
Sekikawa R, Uehara H, Uno K, Sasase T, Nakata Y, Mori Y, Shinohara M, Sugimoto M, Ohta T.   +8 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Effectiveness and safety of Ayurvedic intervention in essential hypertension: a systematic review with meta-analysis. [PDF]

Front Pharmacol
Deshmukh S, Choudhary K, Ahmad A, Reddy G, Rao BCS, Srikanth N, Acharya R.   +6 more
europepmc   +1 more source

The WAIS-Divide deep ice core WD2014 chronology – Part 2: Methane synchronization (68–31 ka BP) and the gas age-ice age difference

, 2014
Christo Buizert, Kurt M. Cuffey, Jeffrey P. Severinghaus, Daniel Baggenstos, T. J. Fudge, Eric J. Steig, Bradley Markle, Mai Winstrup, Rachael H. Rhodes, Edward J. Brook, Todd Sowers, Gary D. Clow, Hai Cheng, R. Lawrence Edwards, Michael Sigl, Joseph R. McConnell, K. C. Taylor   +16 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source