Results 81 to 90 of about 2,012,307 (317)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Changes in the distribution of pre-government and post-government income in Germany 1973 - 1993 : paper presented at the Conference on the Personal Distribution of Income in an International Perspective at the Hanse Institute for Advanced Study in Delmenhorst [PDF]
, 2011 To sum up our findings we come to the following statements. - During the period from 1973 to 1993 inequality of the personal distribution of equivalent pre-government income increased to some extent, as was to be expected given the enormous rise in ...
Becker, Irene, Hauser, Richard
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Sustainable Tourism: Re-Mapping Stakeholders in the Darma Reservoir Tourism Attraction [PDF]
E3S Web of ConferencesThis paper discusses the stakeholders in the tourist area, in this case, the Darma Reservoir, Kuningan Regency, Cirebon, West Java. What is interesting in this study is that the government as a stakeholder is divided into two parties, the government as ...
Kusumawardhani Fajarwaty, Pradhana Arief
doaj +1 more source
The Divided Government in Indonesia
JURNAL POLINTER : KAJIAN POLITIK DAN HUBUNGAN INTERNASIONAL, 2023 Since the fall of the authoritarian system, Indonesia completed the fundamental precondition to democratization through a series of constitutional amendments. As a young democratic country, Indonesia experienced a divided government for the first time under the administration of Joko Widodo. The Divided government is potentially believed to contribute
openaire +1 more source
Policy making in divided government. A pivotal actors model with party discipline [PDF]
This article presents a formal model of policy decision-making in an institutional framework of separation of powers in which the main actors are pivotal political parties with voting discipline. The basic model previously developed from pivotal politics
Josep M. Colomer
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Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Lessons of Election 2000 [PDF]
, 2001 Many people believe that Election 2000 proved only how divided the nation is over politics and policy. In contrast, this study draws six lessons from Election 2000.
John Samples +2 more
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FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source