Results 131 to 140 of about 87,786 (308)

Frequency control circuit for all-digital phase-lock loops [PDF]

open access: yes, 1973
Phase-lock loop references all its operations to fixed high-frequency service clock operating at highest speed which digital circuits permit. Wide-range control circuit provides linear control of frequency of reference signal.
Anderson, T. O.
core   +1 more source

Divided Past, Divided Future

open access: yesAstragalo, 2022
From the early history of Homo sapiens, survival of the fittest depends on co-operation. Humans formed settlements where the hunter-gatherers became warriors, while agrarians became farmers. This created a mutual relationship, where the warriors offered protection in exchange for produce.
openaire   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Apparatus for using a time interval counter to measure frequency stability [PDF]

open access: yes, 1989
An apparatus for measuring the relative stability of two signals is disclosed comprising a means for mixing the two signals down to a beat note sine wave and for producing a beat note square wave whose upcrossings are the same as the sine wave.
Greenhall, Charles A.
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Development and Research of Three-Channel Power Divider for the Decimeter Range

open access: yesVìsnik Nacìonalʹnogo Tehnìčnogo Unìversitetu Ukraïni Kììvsʹkij Polìtehnìčnij Ìnstitut: Serìâ Radìotehnìka, Radìoaparatobuduvannâ
The work is devoted to the development and research of a three-channel decimeter range power divider. Power dividers are widely used in all branches of radio electronics and wireless communication systems, in particular in radio communication systems ...
S. Ye. Fabirovskyy   +4 more
doaj   +1 more source

Comparison of different fractal dimension measuring algorithms for RE-TM M-O films [PDF]

open access: yes
Noise in magneto-optical recording devices is discussed. In general, it appears that either the divider technique or amplitude spectrum technique may be used interchangeably to measure the fractal dimension (D) in the domain wall structure of ideal ...
Bernacki, Bruce E., Mansuripur, M.
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

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