Results 161 to 170 of about 108,961 (314)

Negotiating illness through faith: Religious narratives of cancer etiology among patients and caregivers in Addis Ababa, Ethiopia. [PDF]

PLoS One
Fikre K, Kassegne AB, Tadele G.
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

From Silicosis to Systemic Sclerosis: Erasmus Syndrome in a Young Galamseyer-Case Report. [PDF]

Case Rep Dermatol Med
Gyabaah S, Kyei-Fram S, Mensah KAH, Asamoah OY, Owusu CO, Amenuke DAY, Adu-Boakye Y, Agyei MK.   +7 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Exploring Factors Influencing Decisions to Withdraw Treatment in Iranian Patients With Metastatic Cancer: A Qualitative Content Analysis Study. [PDF]

J Prev Med Public Health
Abadi F, Bijani M, Nouhi E, Rohani C.
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

A discussion of pneumatology and the linguistic turn to practice, with reference to Kevin Vanhoozer’s canonical-linguistic approach to Christian theology

, 2010
This dissertation assesses the pneumatological implications of Kevin Vanhoozer’s canonical-linguistic approach to Christian theology, in the context of the wider issue of recent interest in re-conceiving the cultural-linguistic approach to theology ...
Bellenger, Peter John Russell
core  

Views of suffering among medical students. [PDF]

Philos Ethics Humanit Med
Seeno H, Blaney E, Hu C, Lawler M, Joseph A, Guturu SG, Liefer-Tennant A, Diehl T, Heid C, Kash B, McCarthy J, Krall C.   +11 more
europepmc   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Mapping potential cultural and religious tensions in end-of-life care for Muslim patients: A scoping review. [PDF]

Palliat Med
Muishout G, Post L, El Ayachi S, Ket JCF, van Zuylen L.   +4 more
europepmc   +1 more source